{"id":13774,"date":"2026-09-19T16:40:11","date_gmt":"2026-09-19T16:40:11","guid":{"rendered":"https:\/\/www.lifescienceart.com\/?p=13774"},"modified":"2026-09-19T16:40:11","modified_gmt":"2026-09-19T16:40:11","slug":"personalized-mrna-vaccine-shows-promise-against-melanoma","status":"publish","type":"post","link":"https:\/\/www.lifescienceart.com\/el\/science\/medicine\/personalized-mrna-vaccine-shows-promise-against-melanoma\/","title":{"rendered":"\u03a0\u03c1\u03bf\u03c3\u03c9\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf mRNA \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2 \u03c3\u03c4\u03bf \u03bc\u03b5\u03bb\u03b1\u03bd\u03bf\u03bc\u03ac"},"content":{"rendered":"<h2 class=\"wp-block-heading\">\u03a4\u03bf \u03a0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc mRNA \u0395\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u0394\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03a5\u03c0\u03cc\u03c3\u03c7\u03b5\u03c3\u03b7 \u0395\u03bd\u03b1\u03bd\u03c4\u03af\u03bf\u03bd \u039c\u03b5\u03bb\u03b1\u03bd\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2<\/h2>\n\n<h2 class=\"wp-block-heading\">\u0399\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc<\/h2>\n\n<p class=\"wp-block-paragraph\">\u03a4\u03bf \u03bc\u03b5\u03bb\u03ac\u03bd\u03c9\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03c4\u03cd\u03c0\u03bf\u03c2 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b5\u03cd\u03b8\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b8\u03b1\u03bd\u03ac\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc 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\u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b4\u03b9\u03b1\u03c6\u03cc\u03c1\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03b9\u03ce\u03bd, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5. \u03a4\u03b1 mRNA \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03b1 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03bd \u03c3\u03c4\u03ad\u03bb\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b1\u03b3\u03b3\u03b5\u03bb\u03b9\u03b1\u03c6\u03cc\u03c1\u03bf RNA (mRNA) \u03c3\u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03b4\u03af\u03bd\u03bf\u03c5\u03bd \u03b5\u03bd\u03c4\u03bf\u03bb\u03ae \u03c3\u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03c5\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03bf\u03cd\u03bd \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7.<\/p>\n\n<h2 class=\"wp-block-heading\">\u03a0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc mRNA \u0395\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u03b3\u03b9\u03b1 \u039c\u03b5\u03bb\u03ac\u03bd\u03c9\u03bc\u03b1<\/h2>\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03be\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc mRNA 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\u03a3\u03c4\u03bf\u03c7\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ac \u03bd\u03b5\u03bf\u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03b1, \u03c4\u03bf \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b9\u03b5\u03b3\u03b5\u03af\u03c1\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03c0\u03b9\u03bf \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7.<\/p>\n\n<h2 class=\"wp-block-heading\">\u0391\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03a6\u03ac\u03c3\u03b7\u03c2 2<\/h2>\n\n<p class=\"wp-block-paragraph\">\u039c\u03b9\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03c6\u03ac\u03c3\u03b7\u03c2 2 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03bf\u03cd mRNA \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03bc\u03b5\u03bb\u03ac\u03bd\u03c9\u03bc\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b1, \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03c3\u03c5\u03bd\u03ad\u03b4\u03c1\u03b9\u03bf \u03c4\u03bf\u03c5 American Association for Cancer Research (AACR). \u0397 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03c0\u03b5\u03c1\u03b9\u03b5\u03bb\u03ac\u03bc\u03b2\u03b1\u03bd\u03b5 157 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03bc\u03b5\u03bb\u03ac\u03bd\u03c9\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03af\u03c7\u03b1\u03bd \u03c5\u03c0\u03bf\u03b2\u03bb\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b1\u03c6\u03b1\u03af\u03c1\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5.<\/p>\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c4\u03c5\u03c7\u03b1\u03b9\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03bb\u03ac\u03b2\u03bf\u03c5\u03bd \u03b5\u03af\u03c4\u03b5 \u03c4\u03bf \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc mRNA \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5 \u03c4\u03bf \u03b1\u03bd\u03bf\u03c3\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf Keytruda, \u03b5\u03af\u03c4\u03b5 \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf Keytruda. \u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03cc\u03c4\u03b9 \u03bf \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 Keytruda \u03ae\u03c4\u03b1\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2 \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf Keytruda \u03bc\u03cc\u03bd\u03bf.<\/p>\n\n<p class=\"wp-block-paragraph\">\u03a3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1, \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5 \u03b4\u03cd\u03bf \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1, \u03bf \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03b5\u03af\u03c7\u03b5 \u03b5\u03c0\u03b9\u03c3\u03c4\u03c1\u03ad\u03c8\u03b5\u03b9 \u03c3\u03b5 40\u202f% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03bf\u03c5 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf Keytruda. \u0391\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03c5\u03c1\u03ac \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03bf\u03c5 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b4\u03cd\u03bf, \u03bc\u03cc\u03bd\u03bf \u03c4\u03bf 22\u202f% \u03b5\u03af\u03c7\u03b5 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03af\u03b1. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 \u03bc\u03b5\u03af\u03c9\u03c3\u03b5 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2 \u03ae \u03b8\u03b1\u03bd\u03ac\u03c4\u03bf\u03c5 \u03ba\u03b1\u03c4\u03ac 44\u202f% \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b5 Keytruda.<\/p>\n\n<h2 class=\"wp-block-heading\">\u03a3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03c9\u03bd \u0391\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd<\/h2>\n\n<p class=\"wp-block-paragraph\">\u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c5\u03c4\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03b5\u03bd\u03b8\u03b1\u03c1\u03c1\u03c5\u03bd\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03c4\u03bf \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc mRNA \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03b2\u03ae\u03bc\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b5\u03bb\u03b1\u03bd\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2. \u03a4\u03bf \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03bb\u03ac \u03b1\u03bd\u03b5\u03ba\u03c4\u03cc \u03ba\u03b1\u03b9 \u03ad\u03c7\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7 \u03b8\u03b1\u03bd\u03b1\u03c4\u03b7\u03c6\u03cc\u03c1\u03b1 \u03bd\u03cc\u03c3\u03bf.<\/p>\n\n<h2 class=\"wp-block-heading\">\u0395\u03c0\u03cc\u03bc\u03b5\u03bd\u03b1 \u0392\u03ae\u03bc\u03b1\u03c4\u03b1<\/h2>\n\n<p class=\"wp-block-paragraph\">\u039f\u03b9 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03ad\u03c2 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af \u03c4\u03bf\u03c5 \u03c0\u03b1\u03c1\u03cc\u03bd\u03c4\u03bf\u03c2 \u03bc\u03b9\u03b1 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03c6\u03ac\u03c3\u03b7\u03c2 3 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03bf\u03cd mRNA \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03bc\u03b5\u03bb\u03ac\u03bd\u03c9\u03bc\u03b1. \u0397 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03b1\u03c5\u03c4\u03ae \u03b8\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b8\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03c4\u03b7\u03bd \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03bf\u03bb\u03af\u03bf\u03c5. \u0395\u03ac\u03bd \u03b7 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03c6\u03ac\u03c3\u03b7\u03c2 3 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03ae\u03c2, \u03c4\u03bf \u03b5\u03bc\u03b2\u03cc\u03bb\u03b9\u03bf \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 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