{"id":17300,"date":"2021-05-14T00:22:09","date_gmt":"2021-05-14T00:22:09","guid":{"rendered":"https:\/\/www.lifescienceart.com\/?p=17300"},"modified":"2021-05-14T00:22:09","modified_gmt":"2021-05-14T00:22:09","slug":"dna-based-attack-against-cancer-shows-promise","status":"publish","type":"post","link":"https:\/\/www.lifescienceart.com\/ko\/science\/biotechnology\/dna-based-attack-against-cancer-shows-promise\/","title":{"rendered":"\ud601\uc2e0\uc801\uc778 DNA \uae30\ubc18 \uacf5\uaca9, \uc554\uacfc\uc758 \uc2f8\uc6c0\uc5d0 \ud76c\ub9dd\uc744 \ubc1d\ud600"},"content":{"rendered":"

\ud601\uc2e0\uc801\uc778 DNA \uae30\ubc18 \uc554 \uacf5\uaca9\uc5d0 \uae30\ub300 \ubaa8\uc544<\/h2>\n\n

\uc720\uc804\uc790 \uce58\ub8cc\uc758 \uc774\uc815\ud45c<\/h2>\n\n

\ud0a4\uba54\ub77c \ud56d\uc6d0 \uc218\uc6a9\uccb4 T \uc138\ud3ec \uce58\ub8cc(CAR T \uc138\ud3ec \uce58\ub8cc)\ub77c\ub294 \ud68d\uae30\uc801\uc778 \uce58\ub8cc\ubc95\uc774 \uc554\uacfc\uc758 \uc2f8\uc6c0\uc5d0\uc11c \uc8fc\uc694 \uc774\uc815\ud45c\ub85c \ub5a0\uc62c\ub790\uc2b5\ub2c8\ub2e4. \uc774 \ud601\uc2e0\uc801\uc778 \uc811\uadfc \ubc29\uc2dd\uc5d0\ub294 \ud658\uc790\uc758 \uc790\uac00 \uba74\uc5ed \uc138\ud3ec\ub97c \uc720\uc804\uc801\uc73c\ub85c \ubcc0\ud615\ud558\uc5ec \uc554 \uc138\ud3ec\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \ud30c\uad34\ud558\ub294 \uac83\uc774 \ud3ec\ud568\ub429\ub2c8\ub2e4.<\/p>\n\n

\ud658\uc790\uc758 \uc5ec\uc815<\/h2>\n\n

\ube44\ud638\uc9c0\ud0a8 \ub9bc\ud504\uc885 \uc0dd\uc874\uc790\uc778 \ub514\ub9c8\uc2a4 \ud30c\ub51c\ub77c\ub294 \uc554\uc774 \uc138 \ubc88\uc9f8\ub85c \uc7ac\ubc1c\ud55c \ud6c4 \uc554\uc6b8\ud55c \uc608\ud6c4\uc5d0 \uc9c1\uba74\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uadf8\ub294 CAR T \uc138\ud3ec \uce58\ub8cc\uc5d0\uc11c \ud76c\ub9dd\uc744 \ucc3e\uc558\uc2b5\ub2c8\ub2e4. \uadf8\uc758 T \uc138\ud3ec\ub97c \ucc44\ucde8\ud55c \ud6c4 \uae30\uc220\uc790\ub4e4\uc740 \ub9bc\ud504\uc885 \uc138\ud3ec\uc758 \ud2b9\uc815 \ub2e8\ubc31\uc9c8\uc744 \ucc3e\uc544 \ubd80\ucc29\ud558\ub294 \uc0c8\ub85c\uc6b4 \ud45c\uba74 \uc218\uc6a9\uccb4\ub97c \uc0dd\uc131\ud560 \uc218 \uc788\ub3c4\ub85d \uc0c8\ub85c\uc6b4 \uc720\uc804\uc790\ub97c \uc0bd\uc785\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n

\ub180\ub77c\uc6b4 \uacb0\uacfc<\/h2>\n\n

\ubcc0\ud615\ub41c T \uc138\ud3ec\ub97c \ud22c\uc5ec\ud55c \uc9c0 \uba87 \uc8fc \uc548\uc5d0 \ud30c\ub51c\ub77c\uc758 \ubaa9\uc5d0 \uc0dd\uae34 \uc885\uc591\uc774 \ud06c\uac8c \uc904\uc5b4\ub4e4\uc5c8\uc2b5\ub2c8\ub2e4. 1\ub144 \ud6c4, \uadf8\ub294 \uc5ec\uc804\ud788 \uc554\uc774 \uc5c6\uc5c8\uace0 \uac00\uc871\uacfc \ud568\uaed8 \uc0c8\ub86d\uac8c \uac74\uac15\ud574\uc9c4 \uac83\uc744 \ucd95\ud558\ud588\uc2b5\ub2c8\ub2e4. \ud30c\ub51c\ub77c\uac00 \ucc38\uc5ec\ud55c \uc784\uc0c1 \uc2e4\ud5d8\uc740 \uc57d \uc808\ubc18\uc758 \ud658\uc790\uac00 \uc644\uc804 \uad00\ud574\ub97c \ub2ec\uc131\ud558\ub294 \ub180\ub77c\uc6b4 \uc131\uacf5\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc131\uacf5\ub960\uc740 \uae30\uc874 \uce58\ub8cc\ubc95\uc758 \uc131\uacf5\ub960\ubcf4\ub2e4 \ud6e8\uc52c \ub192\uc2b5\ub2c8\ub2e4.<\/p>\n\n

FDA \uc2b9\uc778 \ubc0f \uc911\uc694\uc131<\/h2>\n\n

\ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA)\uc740 CAR T \uc138\ud3ec \uce58\ub8cc\uc758 \uc7a0\uc7ac\ub825\uc744 \uc778\uc815\ud588\uace0 \uc608\uc2a4\uce74\ub974\ud0c0\ub77c\ub294 \uce58\ub8cc\ubc95 \ubc84\uc804\uc744 \ud2b9\uc815 \uc720\ud615\uc758 B \uc138\ud3ec \ub9bc\ud504\uc885\uc5d0 \uc2b9\uc778\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 FDA\uc5d0\uc11c \uc554 \uce58\ub8cc\uc5d0 \uc2b9\uc778\ud55c \ub450 \ubc88\uc9f8 \uc720\uc804\uc790 \uce58\ub8cc\ubc95\uc77c \ubfd0\uc785\ub2c8\ub2e4.<\/p>\n\n

\uc791\ub3d9 \uba54\ucee4\ub2c8\uc998<\/h2>\n\n

CAR T \uc138\ud3ec \uce58\ub8cc\ub294 \ud658\uc790\uc758 T \uc138\ud3ec\ub97c \uc720\uc804\uc801\uc73c\ub85c \uc870\uc791\ud558\uc5ec \ud0a4\uba54\ub77c \ud56d\uc6d0 \uc218\uc6a9\uccb4(CAR)\ub97c \ubc1c\ud604\ud558\ub3c4\ub85d \ud569\ub2c8\ub2e4. \uc774 \uc218\uc6a9\uccb4\ub294 \uc554 \uc138\ud3ec \ud45c\uba74\uc758 \ud2b9\uc815 \ub2e8\ubc31\uc9c8 \ud45c\uc801\uc744 \uc778\uc2dd\ud558\uace0 \uacb0\ud569\ud558\ub3c4\ub85d \uace0\uc548\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uacb0\ud569\ub418\uba74 T \uc138\ud3ec\uac00 \ud65c\uc131\ud654\ub418\uace0 \uc554 \uc138\ud3ec\ub97c \ud30c\uad34\ud569\ub2c8\ub2e4.<\/p>\n\n

\uc704\ud5d8 \ubc0f \ubd80\uc791\uc6a9<\/h2>\n\n

CAR T \uc138\ud3ec \uce58\ub8cc\uac00 \ud070 \uae30\ub300\ub97c \ubaa8\uc73c\uace0 \uc788\uc9c0\ub9cc \uc77c\ubd80 \uc704\ud5d8\uacfc \ubd80\uc791\uc6a9\uc774 \ub530\ub985\ub2c8\ub2e4. \uc774 \uce58\ub8cc\ubc95\uc740 \ud604\uc7ac \uc801\uc5b4\ub3c4 \ub2e4\ub978 \ub450 \uac00\uc9c0 \ud615\ud0dc\uc758 \uce58\ub8cc\uc5d0 \uc2e4\ud328\ud55c \ud658\uc790\uc5d0\uac8c\ub9cc \uc81c\uacf5\ub429\ub2c8\ub2e4. CAR T \uc138\ud3ec \uce58\ub8cc\ub97c \ud3ec\ud568\ud55c \uba74\uc5ed \uce58\ub8cc\ub294 \uc2e0\uacbd \ub3c5\uc131 \ubc0f \uc0ac\uc774\ud1a0\uce74\uc778 \ubc29\ucd9c \uc99d\ud6c4\uad70(CRS)\uacfc \uac19\uc740 \uc704\ud5d8\ud55c \ubd80\uc791\uc6a9\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. CRS\ub294 \ud65c\uc131 \ubc31\ud608\uad6c\uac00 \uc0ac\uc774\ud1a0\uce74\uc778\uc744 \ubc29\ucd9c\ud588\uc744 \ub54c \ubc1c\uc0dd\ud560 \uc218 \uc788\ub294 \uc5fc\uc99d\uc744 \uc720\ubc1c\ud558\ub294 \uc0dd\uba85\uc744 \uc704\ud611\ud558\ub294 \uc9c8\ud658\uc785\ub2c8\ub2e4.<\/p>\n\n

\uc704\ud5d8\uacfc \uc774\uc810\uc758 \uade0\ud615<\/h2>\n\n

\uc7a0\uc7ac\uc801 \uc704\ud5d8\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 CAR T \uc138\ud3ec \uce58\ub8cc\uc758 \uc774\uc810\uc740 \uc9c4\ud589\ub41c \uc554 \ud658\uc790\uc640 \uce58\ub8cc \uc635\uc158\uc774 \uc81c\ud55c\ub41c \ud658\uc790\uc5d0\uac8c \ubd88\ud3b8\ud568\ubcf4\ub2e4 \ub354 \ud074 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud30c\ub51c\ub77c\ub294 \ubc1c\uc5f4\uacfc \uc77c\uc2dc\uc801\uc778 \uae30\uc5b5 \uc0c1\uc2e4\uacfc \uac19\uc740 \ubd80\uc791\uc6a9\uc744 \uacaa\uc5c8\uc9c0\ub9cc \uacb0\uad6d \ud68c\ubcf5\ub418\uc5b4 \uc815\uc0c1\uc801\uc778 \uac74\uac15\uc73c\ub85c \ub3cc\uc544\uc654\uc2b5\ub2c8\ub2e4.<\/p>\n\n

\ubbf8\ub798\uc5d0 \ub300\ud55c \ud76c\ub9dd<\/h2>\n\n

CAR T \uc138\ud3ec \uce58\ub8cc\ub294 \uc554 \uce58\ub8cc\uc5d0 \ud601\uba85\uc744 \uc77c\uc73c\ud0ac \uac00\ub2a5\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc774\uc804\uc5d0 \uce58\ub8cc \ubd88\uac00\ub2a5\ud55c \uc554\uc5d0 \uac78\ub9b0 \ud658\uc790\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc744 \uc90d\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uce58\ub8cc\uc758 \ud6a8\uacfc\uc640 \uc548\uc804\uc131\uc744 \uac1c\uc120\ud558\uae30 \uc704\ud574 \uc9c0\uc18d\uc801\uc778 \uc5f0\uad6c\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. CAR T \uc138\ud3ec \uce58\ub8cc\uac00 \ub354 \ub110\ub9ac \ucc44\ud0dd\ub428\uc5d0 \ub530\ub77c \uc724\ub9ac\uc801 \uace0\ub824 \uc0ac\ud56d\ub3c4 \uace0\ub824\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n\n

\uc7a5\uae30\uc801\uc778 \uc774\uc810\uacfc \uacfc\uc81c<\/h2>\n\n

CAR T \uc138\ud3ec \uce58\ub8cc\uc758 \uc7a5\uae30\uc801\uc778 \uc774\uc810\uacfc \uacfc\uc81c\ub294 \uc5ec\uc804\ud788 \uc5f0\uad6c\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc790\ub4e4\uc740 \uce58\ub8cc\ubc95\uc744 \ub354\uc6b1 \ud6a8\uacfc\uc801\uc774\uace0 \uc9c0\uc18d\uc801\uc73c\ub85c \ub9cc\ub4dc\ub294 \ubc29\ubc95\uc744 \uc5f0\uad6c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \ub610\ud55c \ubd80\uc791\uc6a9\uc744 \uc904\uc774\uace0 \ud658\uc790\uc758 \ud68c\ubcf5\uc744 \uac1c\uc120\ud558\ub294 \ubc29\ubc95\uc744 \uc5f0\uad6c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n

\ub9de\ucda4\ud615 \uc554 \uce58\ub8cc<\/h2>\n\n

CAR T \uc138\ud3ec \uce58\ub8cc\ub294 \ub9de\ucda4\ud615 \uc554 \uce58\ub8cc\ub97c \ud5a5\ud55c \uc911\uc694\ud55c \ud55c \uac78\uc74c\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uc758\uc0ac\ub294 \uce58\ub8cc\ub97c \ud658\uc790\uc758 \ud2b9\uc815 \uc554 \uc138\ud3ec\uc5d0 \ub9de\uac8c \uc870\uc815\ud568\uc73c\ub85c\uc368 \ub354 \ud6a8\uacfc\uc801\uc774\uace0 \ud45c\uc801\ud654\ub41c \uacb0\uacfc\ub97c \uc5bb\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \uc9c4\ud589 \uc911\uc778 \uc5f0\uad6c\ub294 CAR T \uc138\ud3ec \uce58\ub8cc\uc758 \uc751\uc6a9 \ubd84\uc57c\ub97c \ub354 \uad11\ubc94\uc704\ud55c \uc554 \uc720\ud615\uc73c\ub85c \ud655\ub300\ud558\ub294 \uac83\uc744 \ubaa9\ud45c\ub85c \ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>","protected":false},"excerpt":{"rendered":"

\ud601\uc2e0\uc801\uc778 DNA \uae30\ubc18 \uc554 \uacf5\uaca9\uc5d0 \uae30\ub300 \ubaa8\uc544 \uc720\uc804\uc790 \uce58\ub8cc\uc758 \uc774\uc815\ud45c \ud0a4\uba54\ub77c \ud56d\uc6d0 \uc218\uc6a9\uccb4 T \uc138\ud3ec \uce58\ub8cc(CAR T \uc138\ud3ec \uce58\ub8cc)\ub77c\ub294 \ud68d\uae30\uc801\uc778 \uce58\ub8cc\ubc95\uc774 \uc554\uacfc\uc758 \uc2f8\uc6c0\uc5d0\uc11c \uc8fc\uc694 \uc774\uc815\ud45c\ub85c \ub5a0\uc62c\ub790\uc2b5\ub2c8\ub2e4. \uc774 \ud601\uc2e0\uc801\uc778 \uc811\uadfc \ubc29\uc2dd\uc5d0\ub294…<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1763],"tags":[22778,3368,3369,15186,358],"class_list":["post-17300","post","type-post","status-publish","format-standard","hentry","category-biotechnology","tag-car-t-cell-therapy","tag-immunotherapy","tag-cancer-treatment","tag-gene-therapy","tag-medical-innovation"],"_links":{"self":[{"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/posts\/17300","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/comments?post=17300"}],"version-history":[{"count":1,"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/posts\/17300\/revisions"}],"predecessor-version":[{"id":17301,"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/posts\/17300\/revisions\/17301"}],"wp:attachment":[{"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/media?parent=17300"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/categories?post=17300"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/ko\/wp-json\/wp\/v2\/tags?post=17300"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}