Ola\u011fan\u00fcst\u00fc bir t\u0131bbi geli\u015fmede, melez \u0131rktan bir kad\u0131n, vir\u00fcse do\u011fal olarak diren\u00e7li bir don\u00f6rden k\u00f6k h\u00fccre nakli ald\u0131ktan sonra HIV’den kurtulan d\u00fcnyadaki \u00fc\u00e7\u00fcnc\u00fc ki\u015fi oldu\u011funa inan\u0131l\u0131yor. G\u00f6bek kordonu kan\u0131 kullanan bu yenilik\u00e7i tedavi, geleneksel kemik ili\u011fi nakillerine g\u00f6re \u00f6nemli avantajlar sunuyor.<\/p>\n\n
Bir bebe\u011fin do\u011fumunda toplanan g\u00f6bek kordonu kan\u0131, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi i\u00e7in gerekli olan her t\u00fcrl\u00fc kan h\u00fccresine d\u00f6n\u00fc\u015febilen yeti\u015fkin hematopoietik k\u00f6k h\u00fccreler i\u00e7erir. Don\u00f6r ve al\u0131c\u0131 aras\u0131nda yak\u0131n bir e\u015fle\u015fme gerektiren kemik ili\u011fi nakillerinden farkl\u0131 olarak, g\u00f6bek kordonu kan\u0131 don\u00f6rlerinin bu kadar yak\u0131n e\u015fle\u015fmi\u015f olmalar\u0131 gerekmez, bu da onu nadir doku tipine sahip hastalar i\u00e7in daha eri\u015filebilir bir se\u00e7enek haline getirir.<\/p>\n\n
Melez \u0131rktan bir kad\u0131n\u0131n g\u00f6bek kordonu kan\u0131yla ba\u015far\u0131l\u0131 bir \u015fekilde tedavi edilmesi \u00f6zellikle \u00f6nemlidir, \u00e7\u00fcnk\u00fc HIV orant\u0131s\u0131z bir \u015fekilde \u0131rksal ve etnik az\u0131nl\u0131klar\u0131 etkiler. Ek olarak, hastan\u0131n kad\u0131n olmas\u0131, klinik \u00e7al\u0131\u015fmalarda genellikle yeterince temsil edilmeyen kad\u0131nlar i\u00e7in bu tedavinin potansiyel faydalar\u0131n\u0131 vurgulamaktad\u0131r.<\/p>\n\n
G\u00f6r\u00fcn\u00fc\u015fe g\u00f6re k\u00f6k h\u00fccre nakilleri kullan\u0131larak HIV’den tedavi edilen \u00fc\u00e7 hastan\u0131n tamam\u0131 kansere de sahipti ve hayatlar\u0131n\u0131 kurtarmak i\u00e7in nakillere ihtiya\u00e7lar\u0131 vard\u0131. Bu, g\u00f6bek kordonu kan\u0131 naklinin, hem HIV hem de l\u00f6semi gibi agresif kanserlerle kar\u015f\u0131 kar\u015f\u0131ya olan hastalar i\u00e7in \u00e7ift y\u00f6nl\u00fc bir fayda sa\u011flayabilece\u011fini d\u00fc\u015f\u00fcnd\u00fcrmektedir.<\/p>\n\n
Son tedavi, kanseri i\u00e7in g\u00f6bek kordonu k\u00f6k h\u00fccre nakli alacak toplam 25 HIV hastas\u0131n\u0131 takip edecek daha b\u00fcy\u00fck bir \u00e7al\u0131\u015fman\u0131n bir par\u00e7as\u0131d\u0131r. Tedavi umut verici olsa da hen\u00fcz yayg\u0131n olarak mevcut de\u011fildir ve muhtemelen ba\u015flang\u0131\u00e7ta yaln\u0131zca agresif kanserleri olan ki\u015filer i\u00e7in ge\u00e7erli olacakt\u0131r.<\/p>\n\n
Mevcut s\u0131n\u0131rlamalara ra\u011fmen, bu tedavinin ba\u015far\u0131s\u0131, d\u00fcnya \u00e7ap\u0131nda HIV ile ya\u015fayan milyonlarca insan\u0131n hayat\u0131 \u00fczerinde d\u00f6n\u00fc\u015ft\u00fcr\u00fcc\u00fc bir etkiye sahip olabilir. Ara\u015ft\u0131rmac\u0131lar, ABD’de y\u0131lda yakla\u015f\u0131k 50 hastan\u0131n bu prosed\u00fcrden faydalanabilece\u011fini tahmin ediyor ve k\u0131smen e\u015fle\u015fen g\u00f6bek kordonu kan\u0131 greftlerini kullanabilme ihtimali, bu hastalar i\u00e7in uygun don\u00f6r bulma olas\u0131l\u0131\u011f\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde art\u0131r\u0131yor.<\/p>\n\n
Devam eden ara\u015ft\u0131rmalar, tedavi rejimini optimize etmeye, hasta uygunluk kriterlerini geni\u015fletmeye ve prosed\u00fcr\u00fc daha yayg\u0131n olarak eri\u015filebilir hale getirmeye odaklanacakt\u0131r. S\u00fcrekli geli\u015fmelerle, g\u00f6bek kordonu kan\u0131 nakli, hem HIV hem de kanserle kar\u015f\u0131 kar\u015f\u0131ya olan giderek artan say\u0131da ki\u015fi i\u00e7in hayat kurtar\u0131c\u0131 bir se\u00e7enek haline gelme potansiyeline sahiptir.<\/p>","protected":false},"excerpt":{"rendered":"
HIV’den G\u00f6bek Kordonu Kan\u0131 ile \u0130yile\u015fen \u0130lk Kad\u0131n \u00c7\u0131\u011f\u0131r A\u00e7an Tedavi, Farkl\u0131 Hasta Pop\u00fclasyonlar\u0131 \u0130\u00e7in Umut Vaat Ediyor Ola\u011fan\u00fcst\u00fc bir t\u0131bbi geli\u015fmede, melez \u0131rktan bir kad\u0131n, vir\u00fcse do\u011fal olarak diren\u00e7li…<\/p>\n","protected":false},"author":1,"featured_media":24007,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1862],"tags":[4788,7009,3369,7663,6334,7662],"class_list":["post-4175","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-research","tag-hiv","tag-womens-health","tag-cancer-treatment","tag-mixed-race","tag-stem-cell-transplant","tag-umbilical-cord-blood"],"_links":{"self":[{"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/posts\/4175","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/comments?post=4175"}],"version-history":[{"count":1,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/posts\/4175\/revisions"}],"predecessor-version":[{"id":4176,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/posts\/4175\/revisions\/4176"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/media\/24007"}],"wp:attachment":[{"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/media?parent=4175"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/categories?post=4175"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/tags?post=4175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}