{"id":4807,"date":"2024-08-14T21:14:38","date_gmt":"2024-08-14T21:14:38","guid":{"rendered":"https:\/\/www.lifescienceart.com\/?p=4807"},"modified":"2024-08-14T21:14:38","modified_gmt":"2024-08-14T21:14:38","slug":"allergies-linked-to-reduced-risk-of-sars-cov-2-infection","status":"publish","type":"post","link":"https:\/\/www.lifescienceart.com\/tr\/science\/health-and-medicine\/allergies-linked-to-reduced-risk-of-sars-cov-2-infection\/","title":{"rendered":"Alerjiler SARS-CoV-2 Enfeksiyonu Riskini Azalt\u0131yor"},"content":{"rendered":"

Alerjiler SARS-CoV-2 Enfeksiyonu Riskini Azalt\u0131yor<\/h2>\n\n

\u00d6nemli Bulgular<\/h2>\n\n

Ulusal Sa\u011fl\u0131k Enstit\u00fcleri (NIH) taraf\u0131ndan y\u00fcr\u00fct\u00fclen kapsaml\u0131 bir \u00e7al\u0131\u015fma, alerjiler ve SARS-CoV-2 enfeksiyonu riski aras\u0131ndaki ili\u015fki hakk\u0131nda ilgi \u00e7ekici bulgular ortaya \u00e7\u0131kard\u0131. \u00c7al\u0131\u015fma, g\u0131da alerjisi olan ki\u015filerin vir\u00fcse yakalanma olas\u0131l\u0131\u011f\u0131n\u0131n \u00f6nemli \u00f6l\u00e7\u00fcde daha d\u00fc\u015f\u00fck oldu\u011funu ortaya \u00e7\u0131kard\u0131. Bu ke\u015fif, belirli ba\u011f\u0131\u015f\u0131kl\u0131k tepkilerinin SARS-CoV-2’ye kar\u015f\u0131 potansiyel koruyucu etkilerini vurgulamaktad\u0131r.<\/p>\n\n

G\u0131da Alerjilerinin SARS-CoV-2 Enfeksiyonuna Etkisi<\/h2>\n\n

NIH \u00e7al\u0131\u015fmas\u0131, 1.400 hanede 4.000’den fazla kat\u0131l\u0131mc\u0131dan, re\u015fit olmayanlar da dahil olmak \u00fczere, veri analiz etti. Sonu\u00e7lar, g\u0131da alerjisi olan ki\u015filerin SARS-CoV-2 ile enfekte olma riskinin, alerjisi olmayanlara k\u0131yasla %50 daha d\u00fc\u015f\u00fck oldu\u011funu g\u00f6stermi\u015ftir. Bu g\u00f6zlem, g\u0131da alerjilerinin vir\u00fcse kar\u015f\u0131 bir derece koruma sa\u011flayabilece\u011fini d\u00fc\u015f\u00fcnd\u00fcrmektedir.<\/p>\n\n

Obezite ve V\u00fccut Kitle \u0130ndeksinin (VK\u0130) Etkisi<\/h2>\n\n

G\u0131da alerjilerinin koruyucu etkisinin aksine, \u00e7al\u0131\u015fma obezitenin ve y\u00fcksek v\u00fccut kitle indeksinin (VK\u0130) SARS-CoV-2 enfeksiyonu riskinin artmas\u0131yla ili\u015fkili oldu\u011funu buldu. Bu bulgu, genel sa\u011fl\u0131k ve viral enfeksiyonlara kar\u015f\u0131 duyarl\u0131l\u0131\u011f\u0131 azaltmak i\u00e7in sa\u011fl\u0131kl\u0131 bir kiloyu koruma \u00f6nemini vurgulamaktad\u0131r.<\/p>\n\n

Ast\u0131m ve Egzama: Artan Enfeksiyon Riski Yok<\/h2>\n\n

\u00d6nceki varsay\u0131mlar\u0131n aksine, \u00e7al\u0131\u015fma ast\u0131m ve egzman\u0131n SARS-CoV-2 enfeksiyonu riskini art\u0131rmad\u0131\u011f\u0131n\u0131 ortaya \u00e7\u0131kard\u0131. Bu bulgu, solunum rahats\u0131zl\u0131klar\u0131n\u0131n viral enfeksiyon riskini do\u011fas\u0131 gere\u011fi art\u0131rd\u0131\u011f\u0131 fikrine meydan okumaktad\u0131r.<\/p>\n\n

Tip \u0130ki \u0130ltihap ve ACE2 Resept\u00f6r\u00fc<\/h2>\n\n

Ara\u015ft\u0131rmac\u0131lar, egzama ve baz\u0131 ast\u0131m t\u00fcrleri gibi alerjik durumlarla ili\u015fkili yayg\u0131n bir ba\u011f\u0131\u015f\u0131kl\u0131k yan\u0131t\u0131 olan tip iki iltihab\u0131n SARS-CoV-2 enfeksiyonu riskini azaltmada rol oynayabilece\u011fini d\u00fc\u015f\u00fcn\u00fcyorlar. Tip iki iltihab\u0131n, hava yolu h\u00fccrelerinin y\u00fczeyindeki ACE2 resept\u00f6r\u00fcn\u00fcn seviyelerini azaltt\u0131\u011f\u0131 d\u00fc\u015f\u00fcn\u00fclmektedir. ACE2 resept\u00f6r\u00fc, vir\u00fcs\u00fcn h\u00fccreleri enfekte etmesini sa\u011flayan SARS-CoV-2 sivri u\u00e7lu protein i\u00e7in birincil giri\u015f noktas\u0131d\u0131r. ACE2 resept\u00f6rlerinin say\u0131s\u0131n\u0131 azaltarak, tip iki iltihap, vir\u00fcs\u00fcn h\u00fccrelere girme ve onlar\u0131 enfekte etme yetene\u011fini s\u0131n\u0131rlayabilir.<\/p>\n\n

Koruma Mekanizmalar\u0131<\/h2>\n\n

Alerjisi olan ki\u015filerde SARS-CoV-2 enfeksiyonu riskinin azalmas\u0131n\u0131n alt\u0131nda yatan kesin mekanizmalar hen\u00fcz tam olarak a\u00e7\u0131klanmam\u0131\u015f olsa da, ara\u015ft\u0131rmac\u0131lar birka\u00e7 potansiyel fakt\u00f6r\u00fc ara\u015ft\u0131r\u0131yorlar. Bir olas\u0131l\u0131k, alerjilerin vir\u00fcs\u00fcn \u00e7o\u011falma yetene\u011fini engelleyen \u00f6zel ba\u011f\u0131\u015f\u0131kl\u0131k molek\u00fcllerinin \u00fcretimini tetiklemesidir. Bir di\u011fer hipotez ise alerjik durumlar\u0131n ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin vir\u00fcs\u00fc daha etkili bir \u015fekilde tan\u0131ma ve temizleme yetene\u011fini geli\u015ftirebilece\u011fini \u00f6ne s\u00fcrmektedir.<\/p>\n\n

Halk Sa\u011fl\u0131\u011f\u0131 \u0130\u00e7in Etkileri<\/h2>\n\n

NIH \u00e7al\u0131\u015fmas\u0131n\u0131n bulgular\u0131, \u00e7ocuklar\u0131 a\u015f\u0131laman\u0131n ve SARS-CoV-2 enfeksiyonunu \u00f6nlemek i\u00e7in kapsaml\u0131 halk sa\u011fl\u0131\u011f\u0131 \u00f6nlemlerini uygulaman\u0131n \u00f6nemini vurgulamaktad\u0131r. A\u015f\u0131lama, bireyleri ve savunmas\u0131z n\u00fcfuslar\u0131 vir\u00fcsten korumak i\u00e7in en etkili yol olmaya devam etmektedir.<\/p>\n\n

Yeni Ara\u015ft\u0131rma Y\u00f6nleri<\/h2>\n\n

\u00c7al\u0131\u015fman\u0131n bulgular\u0131, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi, alerjik durumlar ve viral enfeksiyonlar aras\u0131ndaki karma\u015f\u0131k etkile\u015fimin ara\u015ft\u0131r\u0131lmas\u0131 i\u00e7in yeni yollar a\u00e7maktad\u0131r. Gelecekteki \u00e7al\u0131\u015fmalar, alerjisi olan ki\u015filerde g\u00f6zlemlenen koruyucu etkilerden sorumlu spesifik ba\u011f\u0131\u015f\u0131kl\u0131k mekanizmalar\u0131n\u0131 belirlemeyi ama\u00e7layacakt\u0131r. Ayr\u0131ca ara\u015ft\u0131rmac\u0131lar, SARS-CoV-2 ve di\u011fer viral enfeksiyonlara kar\u015f\u0131 korumay\u0131 geli\u015ftirmek i\u00e7in ba\u011f\u0131\u015f\u0131kl\u0131k tepkilerini d\u00fczenlemenin potansiyel faydalar\u0131n\u0131 ara\u015ft\u0131racaklard\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"

Alerjiler SARS-CoV-2 Enfeksiyonu Riskini Azalt\u0131yor \u00d6nemli Bulgular Ulusal Sa\u011fl\u0131k Enstit\u00fcleri (NIH) taraf\u0131ndan y\u00fcr\u00fct\u00fclen kapsaml\u0131 bir \u00e7al\u0131\u015fma, alerjiler ve SARS-CoV-2 enfeksiyonu riski aras\u0131ndaki ili\u015fki hakk\u0131nda ilgi \u00e7ekici bulgular ortaya \u00e7\u0131kard\u0131. \u00c7al\u0131\u015fma,…<\/p>\n","protected":false},"author":6,"featured_media":24056,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[463],"tags":[8645,7149,8646,178,8490,1858,8647],"class_list":["post-4807","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-and-medicine","tag-allergies","tag-immunity","tag-immune-response","tag-public-health","tag-infection","tag-sars-cov-2","tag-viral-infection"],"_links":{"self":[{"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/posts\/4807","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/comments?post=4807"}],"version-history":[{"count":1,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/posts\/4807\/revisions"}],"predecessor-version":[{"id":4808,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/posts\/4807\/revisions\/4808"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/media\/24056"}],"wp:attachment":[{"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/media?parent=4807"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/categories?post=4807"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/tr\/wp-json\/wp\/v2\/tags?post=4807"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}