{"id":11511,"date":"2024-09-30T23:29:20","date_gmt":"2024-09-30T23:29:20","guid":{"rendered":"https:\/\/www.lifescienceart.com\/?p=11511"},"modified":"2024-09-30T23:29:20","modified_gmt":"2024-09-30T23:29:20","slug":"lab-on-a-chip-a-revolutionary-medical-diagnostic-tool","status":"publish","type":"post","link":"https:\/\/www.lifescienceart.com\/vi\/science\/medical-technology\/lab-on-a-chip-a-revolutionary-medical-diagnostic-tool\/","title":{"rendered":"Ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip: Cu\u1ed9c c\u00e1ch m\u1ea1ng trong ch\u1ea9n \u0111o\u00e1n y khoa"},"content":{"rendered":"<h2 class=\"wp-block-heading\">Ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip: C\u00f4ng c\u1ee5 ch\u1ea9n \u0111o\u00e1n y khoa mang t\u00ednh c\u00e1ch m\u1ea1ng<\/h2>\n\n<h2 class=\"wp-block-heading\">Ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip l\u00e0 g\u00ec?<\/h2>\n\n<p>Ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip, hay c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 thi\u1ebft b\u1ecb vi l\u01b0u, l\u00e0 m\u1ed9t ph\u00f2ng th\u00ed nghi\u1ec7m thu nh\u1ecf c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n c\u00e1c ch\u1ea9n \u0111o\u00e1n y khoa ph\u1ee9c t\u1ea1p tr\u00ean m\u1ed9t n\u1ec1n t\u1ea3ng nh\u1ecf g\u1ecdn c\u00f3 th\u1ec3 mang theo. C\u00e1c thi\u1ebft b\u1ecb n\u00e0y th\u01b0\u1eddng kh\u00f4ng l\u1edbn h\u01a1n m\u1ed9t con tem v\u00e0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ph\u00e2n t\u00edch nhi\u1ec1u lo\u1ea1i m\u1eabu sinh h\u1ecdc, ch\u1eb3ng h\u1ea1n nh\u01b0 m\u00e1u, n\u01b0\u1edbc ti\u1ec3u v\u00e0 n\u01b0\u1edbc b\u1ecdt.<\/p>\n\n<h2 class=\"wp-block-heading\">Ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o?<\/h2>\n\n<p>C\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip s\u1eed d\u1ee5ng vi l\u01b0u, khoa h\u1ecdc v\u1ec1 vi\u1ec7c thao t\u00e1c c\u00e1c th\u1ec3 t\u00edch ch\u1ea5t l\u1ecfng nh\u1ecf, \u0111\u1ec3 th\u1ef1c hi\u1ec7n c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n. C\u00e1c thi\u1ebft b\u1ecb n\u00e0y th\u01b0\u1eddng \u0111\u01b0\u1ee3c l\u00e0m b\u1eb1ng nh\u1ef1a ho\u1eb7c th\u1ee7y tinh v\u00e0 ch\u1ee9a m\u1ed9t m\u1ea1ng l\u01b0\u1edbi c\u00e1c k\u00eanh v\u00e0 khoang nh\u1ecf. C\u00e1c k\u00eanh n\u00e0y \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 ki\u1ec3m so\u00e1t d\u00f2ng ch\u1ea3y c\u1ee7a ch\u1ea5t l\u1ecfng v\u00e0 thu\u1ed1c th\u1eed, cho ph\u00e9p ph\u00e2n t\u00edch ch\u00ednh x\u00e1c v\u00e0 nhanh ch\u00f3ng.<\/p>\n\n<h2 class=\"wp-block-heading\">C\u00e1c \u1ee9ng d\u1ee5ng c\u1ee7a c\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip<\/h2>\n\n<p>C\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip c\u00f3 nhi\u1ec1u \u1ee9ng d\u1ee5ng trong ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf nh\u1eefng n\u01a1i xa x\u00f4i v\u00e0 thi\u1ebfu ngu\u1ed3n l\u1ef1c. C\u00e1c thi\u1ebft b\u1ecb n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n nhi\u1ec1u lo\u1ea1i b\u1ec7nh, bao g\u1ed3m c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m, ung th\u01b0 v\u00e0 c\u00e1c r\u1ed1i lo\u1ea1n di truy\u1ec1n. Ch\u00fang c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 theo d\u00f5i s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0 theo d\u00f5i hi\u1ec7u qu\u1ea3 c\u1ee7a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb.<\/p>\n\n<h2 class=\"wp-block-heading\">Nh\u1eefng \u01b0u \u0111i\u1ec3m c\u1ee7a c\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip<\/h2>\n\n<p>C\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip c\u00f3 m\u1ed9t s\u1ed1 \u01b0u \u0111i\u1ec3m so v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p x\u00e9t nghi\u1ec7m truy\u1ec1n th\u1ed1ng:<\/p>\n\n<ul class=\"wp-block-list\">\n<li><strong>T\u00ednh di \u0111\u1ed9ng:<\/strong> C\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip c\u00f3 k\u00edch th\u01b0\u1edbc nh\u1ecf v\u00e0 tr\u1ecdng l\u01b0\u1ee3ng nh\u1eb9, gi\u00fap d\u1ec5 d\u00e0ng v\u1eadn chuy\u1ec3n v\u00e0 s\u1eed d\u1ee5ng \u1edf nh\u1eefng n\u01a1i xa x\u00f4i.<\/li>\n<li><strong>K\u1ebft qu\u1ea3 nhanh ch\u00f3ng:<\/strong> C\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip c\u00f3 th\u1ec3 cung c\u1ea5p k\u1ebft qu\u1ea3 trong v\u00e0i ph\u00fat ho\u1eb7c v\u00e0i gi\u1edd, so v\u1edbi nhi\u1ec1u ng\u00e0y ho\u1eb7c nhi\u1ec1u tu\u1ea7n \u0111\u1ed1i v\u1edbi c\u00e1c x\u00e9t nghi\u1ec7m trong ph\u00f2ng th\u00ed nghi\u1ec7m truy\u1ec1n th\u1ed1ng.<\/li>\n<li><strong>Chi ph\u00ed th\u1ea5p:<\/strong> C\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip t\u01b0\u01a1ng \u0111\u1ed1i r\u1ebb \u0111\u1ec3 s\u1ea3n xu\u1ea5t, gi\u00fap c\u00e1c nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe \u1edf c\u00e1c n\u01b0\u1edbc \u0111ang ph\u00e1t tri\u1ec3n c\u00f3 th\u1ec3 ti\u1ebfp c\u1eadn \u0111\u01b0\u1ee3c.<\/li>\n<li><strong>D\u1ec5 s\u1eed d\u1ee5ng:<\/strong> C\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf th\u00e2n thi\u1ec7n v\u1edbi ng\u01b0\u1eddi d\u00f9ng, cho ph\u00e9p nh\u00e2n vi\u00ean y t\u1ebf c\u00f3 tr\u00ecnh \u0111\u1ed9 \u0111\u00e0o t\u1ea1o t\u1ed1i thi\u1ec3u c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n ph\u1ee9c t\u1ea1p.<\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\">Nh\u1eefng th\u00e1ch th\u1ee9c c\u1ee7a c\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip<\/h2>\n\n<p>M\u1eb7c d\u00f9 c\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip c\u00f3 ti\u1ec1m n\u0103ng to l\u1edbn, nh\u01b0ng v\u1eabn c\u00f2n m\u1ed9t s\u1ed1 th\u00e1ch th\u1ee9c c\u1ea7n ph\u1ea3i gi\u1ea3i quy\u1ebft:<\/p>\n\n<ul class=\"wp-block-list\">\n<li><strong>\u0110\u1ed9 nh\u1ea1y:<\/strong> \u0110\u00f4i khi, c\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip c\u00f3 th\u1ec3 k\u00e9m nh\u1ea1y h\u01a1n so v\u1edbi c\u00e1c x\u00e9t nghi\u1ec7m trong ph\u00f2ng th\u00ed nghi\u1ec7m truy\u1ec1n th\u1ed1ng, khi\u1ebfn ch\u00fang \u00edt ph\u00f9 h\u1ee3p h\u01a1n \u0111\u1ec3 ph\u00e1t hi\u1ec7n m\u1ed9t s\u1ed1 b\u1ec7nh nh\u1ea5t \u0111\u1ecbnh.<\/li>\n<li><strong>T\u00ednh \u0111a h\u1ee3p:<\/strong> C\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip th\u01b0\u1eddng \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 th\u1ef1c hi\u1ec7n m\u1ed9t x\u00e9t nghi\u1ec7m duy nh\u1ea5t t\u1ea1i m\u1ed9t th\u1eddi \u0111i\u1ec3m. T\u00ednh \u0111a h\u1ee3p, kh\u1ea3 n\u0103ng th\u1ef1c hi\u1ec7n nhi\u1ec1u x\u00e9t nghi\u1ec7m c\u00f9ng l\u00fac, v\u1eabn l\u00e0 m\u1ed9t th\u00e1ch th\u1ee9c \u0111\u1ed1i v\u1edbi c\u00e1c thi\u1ebft b\u1ecb n\u00e0y.<\/li>\n<li><strong>T\u00ednh t\u00edch h\u1ee3p:<\/strong> Vi\u1ec7c t\u00edch h\u1ee3p c\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip v\u1edbi c\u00e1c h\u1ec7 th\u1ed1ng ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe kh\u00e1c, ch\u1eb3ng h\u1ea1n nh\u01b0 h\u1ed3 s\u01a1 s\u1ee9c kh\u1ecfe \u0111i\u1ec7n t\u1eed, v\u1eabn \u0111ang trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n.<\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\">T\u01b0\u01a1ng lai c\u1ee7a c\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip<\/h2>\n\n<p>C\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip l\u00e0 m\u1ed9t l\u0129nh v\u1ef1c \u0111ang ph\u00e1t tri\u1ec3n nhanh ch\u00f3ng, c\u00f3 ti\u1ec1m n\u0103ng to l\u1edbn trong vi\u1ec7c c\u00e1ch m\u1ea1ng h\u00f3a h\u1ec7 th\u1ed1ng ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe. Khi nghi\u00ean c\u1ee9u ti\u1ebfp t\u1ee5c, ch\u00fang ta c\u00f3 th\u1ec3 mong \u0111\u1ee3i s\u1ebd th\u1ea5y nhi\u1ec1u thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip s\u00e1ng t\u1ea1o v\u00e0 m\u1ea1nh m\u1ebd h\u01a1n c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n vi\u1ec7c ch\u0103m s\u00f3c b\u1ec7nh nh\u00e2n v\u00e0 gi\u00fap ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe d\u1ec5 ti\u1ebfp c\u1eadn h\u01a1n v\u1edbi m\u1ecdi ng\u01b0\u1eddi.<\/p>\n\n<h2 class=\"wp-block-heading\">Vai tr\u00f2 c\u1ee7a George Whitesides trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip<\/h2>\n\n<p>George Whitesides l\u00e0 m\u1ed9t nh\u00e0 ti\u00ean phong v\u1ec1 c\u00f4ng ngh\u1ec7 nano n\u1ed5i ti\u1ebfng, ng\u01b0\u1eddi \u0111\u00e3 \u0111\u00f3ng m\u1ed9t vai tr\u00f2 quan tr\u1ecdng trong s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip. Nghi\u00ean c\u1ee9u c\u1ee7a \u00f4ng v\u1ec1 vi l\u01b0u v\u00e0 h\u00f3a h\u1ecdc b\u1ec1 m\u1eb7t \u0111\u00e3 d\u1eabn \u0111\u1ebfn vi\u1ec7c t\u1ea1o ra c\u00e1c v\u1eadt li\u1ec7u v\u00e0 thi\u1ebft b\u1ecb m\u1edbi, \u0111\u00f3ng vai tr\u00f2 thi\u1ebft y\u1ebfu cho c\u00e1c \u1ee9ng d\u1ee5ng ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip. Nghi\u00ean c\u1ee9u c\u1ee7a Whitesides \u0111\u00e3 gi\u00fap bi\u1ebfn c\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip th\u00e0nh hi\u1ec7n th\u1ef1c v\u00e0 m\u1edf \u0111\u01b0\u1eddng cho vi\u1ec7c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i trong ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe.<\/p>\n\n<h2 class=\"wp-block-heading\">Nh\u1eefng c\u00e2n nh\u1eafc v\u1ec1 m\u1eb7t \u0111\u1ea1o \u0111\u1ee9c \u0111\u1ed1i v\u1edbi c\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip<\/h2>\n\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c thi\u1ebft b\u1ecb ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip \u0111\u1eb7t ra nh\u1eefng c\u00e2n nh\u1eafc quan tr\u1ecdng v\u1ec1 m\u1eb7t \u0111\u1ea1o \u0111\u1ee9c. C\u00e1c thi\u1ebft b\u1ecb n\u00e0y c\u00f3 ti\u1ec1m n\u0103ng l\u00e0m cho ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe d\u1ec5 ti\u1ebfp c\u1eadn v\u00e0 gi\u00e1 c\u1ea3 ph\u1ea3i ch\u0103ng h\u01a1n, nh\u01b0ng ch\u00fang c\u0169ng c\u00f3 kh\u1ea3 n\u0103ng b\u1ecb s\u1eed d\u1ee5ng cho c\u00e1c m\u1ee5c \u0111\u00edch phi \u0111\u1ea1o \u0111\u1ee9c, ch\u1eb3ng h\u1ea1n nh\u01b0 ph\u00e2n bi\u1ec7t \u0111\u1ed1i x\u1eed v\u1ec1 m\u1eb7t di truy\u1ec1n ho\u1eb7c ph\u00e1t tri\u1ec3n v\u0169 kh\u00ed sinh h\u1ecdc. \u0110i\u1ec1u quan tr\u1ecdng l\u00e0 ph\u1ea3i ph\u00e1t tri\u1ec3n c\u00e1c h\u01b0\u1edbng d\u1eabn \u0111\u1ea1o \u0111\u1ee9c v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o r\u1eb1ng c\u00f4ng ngh\u1ec7 n\u00e0y \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng v\u00ec l\u1ee3i \u00edch c\u1ee7a nh\u00e2n lo\u1ea1i ch\u1ee9 kh\u00f4ng ph\u1ea3i \u0111\u1ec3 g\u00e2y b\u1ea5t l\u1ee3i.<\/p>","protected":false},"excerpt":{"rendered":"<p>Ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip: C\u00f4ng c\u1ee5 ch\u1ea9n \u0111o\u00e1n y khoa mang t\u00ednh c\u00e1ch m\u1ea1ng Ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean m\u1ed9t con chip l\u00e0 g\u00ec? Ph\u00f2ng th\u00ed nghi\u1ec7m tr\u00ean&hellip;<\/p>\n","protected":false},"author":1,"featured_media":24489,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[507],"tags":[2569,7348,15580,1866],"class_list":["post-11511","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-technology","tag-nanotechnology","tag-healthcare-innovation","tag-lab-on-a-chip","tag-medical-diagnostics"],"_links":{"self":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/11511","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/comments?post=11511"}],"version-history":[{"count":2,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/11511\/revisions"}],"predecessor-version":[{"id":24490,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/11511\/revisions\/24490"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/media\/24489"}],"wp:attachment":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/media?parent=11511"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/categories?post=11511"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/tags?post=11511"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}