{"id":15634,"date":"2022-08-20T03:33:16","date_gmt":"2022-08-20T03:33:16","guid":{"rendered":"https:\/\/www.lifescienceart.com\/?p=15634"},"modified":"2022-08-20T03:33:16","modified_gmt":"2022-08-20T03:33:16","slug":"herpes-virus-molecular-structure-therapeutic-potential","status":"publish","type":"post","link":"https:\/\/www.lifescienceart.com\/vi\/science\/virology\/herpes-virus-molecular-structure-therapeutic-potential\/","title":{"rendered":"Virus herpes: M\u1ed9t k\u1ef3 quan ph\u00e2n t\u1eed v\u1edbi ti\u1ec1m n\u0103ng \u0111i\u1ec1u tr\u1ecb"},"content":{"rendered":"

Virus herpes: M\u1ed9t k\u1ef3 quan ph\u00e2n t\u1eed v\u1edbi ti\u1ec1m n\u0103ng \u0111i\u1ec1u tr\u1ecb<\/h2>\n\n

C\u1ea5u tr\u00fac ph\u00e2n t\u1eed c\u1ee7a virus herpes<\/h2>\n\n

Virus herpes simplex (HSV), th\u01b0\u1eddng \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 herpes, l\u00e0 m\u1ed9t lo\u1ea1i virus ph\u1ee9c t\u1ea1p \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn m\u1ed9t b\u1ed9 ph\u1eadn l\u1edbn d\u00e2n s\u1ed1 to\u00e0n c\u1ea7u. C\u00e1c nh\u00e0 khoa h\u1ecdc g\u1ea7n \u0111\u00e2y \u0111\u00e3 xem x\u00e9t k\u1ef9 h\u01a1n c\u1ea5u tr\u00fac ph\u00e2n t\u1eed c\u1ee7a HSV b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng m\u1ed9t k\u1ef9 thu\u1eadt g\u1ecdi l\u00e0 k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed l\u1ea1nh, cho ph\u00e9p h\u1ecd h\u00ecnh dung c\u00e1c ph\u00e2n t\u1eed sinh h\u1ecdc r\u1ea5t chi ti\u1ebft.<\/p>\n\n

K\u1ebft qu\u1ea3, \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Science, ti\u1ebft l\u1ed9 r\u1eb1ng c\u00e1c v\u1ecf b\u1ecdc c\u1ee7a HSV, nh\u1eefng l\u1ed3ng protein bao b\u1ecdc DNA c\u1ee7a n\u00f3, \u0111\u01b0\u1ee3c s\u1eafp x\u1ebfp ph\u1ee9c t\u1ea1p v\u1edbi kho\u1ea3ng 3.000 protein. C\u00e1c v\u1ecf b\u1ecdc n\u00e0y r\u1ea5t c\u1ea7n thi\u1ebft \u0111\u1ec3 virus \u0111\u01b0a v\u1eadt li\u1ec7u di truy\u1ec1n c\u1ee7a m\u00ecnh v\u00e0o c\u00e1c t\u1ebf b\u00e0o ch\u1ee7 v\u00e0 b\u1eaft \u0111\u1ea7u sao ch\u00e9p.<\/p>\n\n

C\u01a1 ch\u1ebf nhi\u1ec5m tr\u00f9ng herpes<\/h2>\n\n

Kh\u00f4ng gi\u1ed1ng nh\u01b0 vi khu\u1ea9n, c\u00e1c lo\u1ea1i virus nh\u01b0 HSV kh\u00f4ng th\u1ec3 t\u1ef1 sinh s\u1ea3n. Thay v\u00e0o \u0111\u00f3, ch\u00fang chi\u1ebfm gi\u1eef c\u00e1c t\u1ebf b\u00e0o ch\u1ee7 b\u1eb1ng c\u00e1ch ti\u00eam DNA c\u1ee7a ch\u00fang v\u00e0o \u0111\u00f3. C\u00e1c v\u1ecf b\u1ecdc c\u1ee7a HSV \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh n\u00e0y, cung c\u1ea5p m\u1ed9t l\u1edbp v\u1ecf b\u1ea3o v\u1ec7 cho b\u1ed9 gen c\u1ee7a virus v\u00e0 t\u1ea1o \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i cho s\u1ef1 x\u00e2m nh\u1eadp c\u1ee7a n\u00f3 v\u00e0o t\u1ebf b\u00e0o ch\u1ee7.<\/p>\n\n

Hi\u1ec3u \u0111\u01b0\u1ee3c c\u1ea5u tr\u00fac v\u00e0 ch\u1ee9c n\u0103ng c\u1ee7a v\u1ecf b\u1ecdc l\u00e0 r\u1ea5t quan tr\u1ecdng \u0111\u1ec3 ph\u00e1t tri\u1ec3n c\u00e1c t\u00e1c nh\u00e2n ch\u1ed1ng vi-r\u00fat c\u00f3 th\u1ec3 ng\u0103n ch\u1eb7n kh\u1ea3 n\u0103ng l\u00e2y nhi\u1ec5m t\u1ebf b\u00e0o c\u1ee7a virus. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi cho b\u1ec7nh herpes v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng l\u00e0 c\u00e1c b\u1ec7nh nhi\u1ec5m virus kh\u00e1c.<\/p>\n\n

C\u00e1c \u1ee9ng d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a virus Herpes<\/h2>\n\n

Ngo\u00e0i vai tr\u00f2 c\u1ee7a n\u00f3 trong nhi\u1ec5m tr\u00f9ng herpes, HSV c\u0169ng cho th\u1ea5y tri\u1ec3n v\u1ecdng nh\u01b0 m\u1ed9t t\u00e1c nh\u00e2n \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c kh\u1ed1i u. Kh\u1ea3 n\u0103ng \u0111\u01b0a v\u1eadt li\u1ec7u di truy\u1ec1n v\u00e0o c\u00e1c t\u1ebf b\u00e0o c\u1ee7a v\u1ecf b\u1ecdc khi\u1ebfn n\u00f3 tr\u1edf th\u00e0nh m\u1ed9t vect\u01a1 ti\u1ec1m n\u0103ng \u0111\u1ec3 \u0111\u01b0a c\u00e1c gen ch\u1ed1ng ung th\u01b0.<\/p>\n\n

\u0110\u1ed9t ph\u00e1 trong nghi\u00ean c\u1ee9u v\u1ec1 b\u1ec7nh herpes<\/h2>\n\n

C\u00e1c nghi\u00ean c\u1ee9u k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed l\u1ea1nh m\u1edbi nh\u1ea5t \u0111\u1ea1i di\u1ec7n cho m\u1ed9t b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 \u0111\u00e1ng k\u1ec3 trong nghi\u00ean c\u1ee9u v\u1ec1 b\u1ec7nh herpes. Ch\u00fang cung c\u1ea5p c\u00e1i nh\u00ecn chi ti\u1ebft nh\u1ea5t v\u1ec1 virus cho \u0111\u1ebfn nay, ti\u1ebft l\u1ed9 s\u1ef1 s\u1eafp x\u1ebfp ph\u1ee9c t\u1ea1p c\u1ee7a c\u00e1c protein b\u00ean trong v\u1ecf b\u1ecdc.<\/p>\n\n

Nh\u1eefng ph\u00e1t hi\u1ec7n n\u00e0y m\u1edf \u0111\u01b0\u1eddng cho c\u00e1c nghi\u00ean c\u1ee9u s\u00e2u h\u01a1n v\u1ec1 c\u01a1 ch\u1ebf l\u00e2y nhi\u1ec5m herpes v\u00e0 s\u1ef1 ph\u00e1t tri\u1ec3n c\u00e1c li\u1ec7u ph\u00e1p ch\u1ed1ng vi-r\u00fat m\u1edbi. Ch\u00fang c\u0169ng nh\u1ea5n m\u1ea1nh ti\u1ec1m n\u0103ng c\u1ee7a c\u00e1c k\u1ef9 thu\u1eadt h\u00ecnh \u1ea3nh ti\u00ean ti\u1ebfn trong vi\u1ec7c th\u00fac \u0111\u1ea9y s\u1ef1 hi\u1ec3u bi\u1ebft c\u1ee7a ch\u00fang ta v\u1ec1 c\u00e1c b\u1ec7nh do virus g\u00e2y ra v\u00e0 ph\u00e1t tri\u1ec3n c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi.<\/p>\n\n

H\u01b0\u1edbng nghi\u00ean c\u1ee9u trong t\u01b0\u01a1ng lai<\/h2>\n\n

M\u1eb7c d\u00f9 c\u00e1c nghi\u00ean c\u1ee9u n\u00e0y \u0111\u00e3 l\u00e0m s\u00e1ng t\u1ecf c\u1ea5u tr\u00fac c\u1ee7a v\u1ecf b\u1ecdc herpes, nh\u01b0ng v\u1eabn c\u00f2n nhi\u1ec1u \u0111i\u1ec1u c\u1ea7n t\u00ecm hi\u1ec3u v\u1ec1 c\u00e1ch DNA x\u00e2m nh\u1eadp v\u00e0o nang. C\u00e1c nghi\u00ean c\u1ee9u trong t\u01b0\u01a1ng lai s\u1ebd t\u1eadp trung v\u00e0o vi\u1ec7c l\u00e0m s\u00e1ng t\u1ecf qu\u00e1 tr\u00ecnh n\u00e0y v\u00e0 kh\u00e1m ph\u00e1 c\u00e1c \u1ee9ng d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a HSV.<\/p>\n\n

B\u1eb1ng c\u00e1ch ti\u1ebfp t\u1ee5c nghi\u00ean c\u1ee9u v\u1ec1 s\u1ef1 ph\u1ee9c t\u1ea1p ph\u00e2n t\u1eed c\u1ee7a virus herpes, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u1eb7t m\u1ee5c ti\u00eau \u0111\u1ea1t \u0111\u01b0\u1ee3c s\u1ef1 hi\u1ec3u bi\u1ebft s\u00e2u s\u1eafc h\u01a1n v\u1ec1 sinh h\u1ecdc c\u1ee7a n\u00f3 v\u00e0 ph\u00e1t tri\u1ec3n c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 h\u01a1n cho c\u00e1c b\u1ec7nh nhi\u1ec5m herpes v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng l\u00e0 c\u00e1c b\u1ec7nh kh\u00e1c.<\/p>","protected":false},"excerpt":{"rendered":"

Virus herpes: M\u1ed9t k\u1ef3 quan ph\u00e2n t\u1eed v\u1edbi ti\u1ec1m n\u0103ng \u0111i\u1ec1u tr\u1ecb C\u1ea5u tr\u00fac ph\u00e2n t\u1eed c\u1ee7a virus herpes Virus herpes simplex (HSV), th\u01b0\u1eddng \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 herpes, l\u00e0 m\u1ed9t…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20803],"tags":[20756,20802,8647,6086,20801],"class_list":["post-15634","post","type-post","status-publish","format-standard","hentry","category-virology","tag-molecular-structure","tag-cryo-electron-microscopy","tag-viral-infection","tag-therapeutic-potential","tag-herpes-virus"],"_links":{"self":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/15634","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/comments?post=15634"}],"version-history":[{"count":1,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/15634\/revisions"}],"predecessor-version":[{"id":15635,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/15634\/revisions\/15635"}],"wp:attachment":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/media?parent=15634"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/categories?post=15634"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/tags?post=15634"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}