{"id":18395,"date":"2024-02-07T00:57:51","date_gmt":"2024-02-07T00:57:51","guid":{"rendered":"https:\/\/www.lifescienceart.com\/?p=18395"},"modified":"2024-02-07T00:57:51","modified_gmt":"2024-02-07T00:57:51","slug":"malaria-vaccine-long-awaited-breakthrough","status":"publish","type":"post","link":"https:\/\/www.lifescienceart.com\/vi\/science\/health-and-medicine\/malaria-vaccine-long-awaited-breakthrough\/","title":{"rendered":"V\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t: M\u1ed9t b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 \u0111\u01b0\u1ee3c mong \u0111\u1ee3i t\u1eeb l\u00e2u"},"content":{"rendered":"

V\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t: M\u1ed9t b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 \u0111\u01b0\u1ee3c mong \u0111\u1ee3i t\u1eeb l\u00e2u<\/h2>\n\n

Nh\u1eefng th\u00e1ch th\u1ee9c trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n<\/h2>\n\n

Vi\u1ec7c ph\u00e1t tri\u1ec3n v\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t l\u00e0 m\u1ed9t h\u00e0nh tr\u00ecnh gian nan do s\u1ef1 ph\u1ee9c t\u1ea1p c\u1ee7a k\u00fd sinh tr\u00f9ng s\u1ed1t r\u00e9t. Lo\u1ea1i k\u00fd sinh tr\u00f9ng n\u00e0y c\u00f3 v\u00f2ng \u0111\u1eddi \u0111\u1ed9c \u0111\u00e1o v\u00e0 c\u00f3 th\u1ec3 tr\u1ed1n tr\u00e1nh h\u1ec7 mi\u1ec5n d\u1ecbch. Nh\u1eefng n\u1ed7 l\u1ef1c ban \u0111\u1ea7u nh\u1eb1m t\u1ea1o ra v\u1eafc-xin d\u1ef1a tr\u00ean protein v\u1ecf ngo\u00e0i kh\u00f4ng th\u00e0nh c\u00f4ng, nh\u01b0ng RTS,S \u0111\u00e3 n\u1ed5i l\u00ean nh\u01b0 m\u1ed9t \u1ee9ng c\u1eed vi\u00ean \u0111\u1ea7y tri\u1ec3n v\u1ecdng.<\/p>\n\n

Thi\u1ebfu s\u1ef1 c\u1ea5p b\u00e1ch v\u00e0 t\u00e0i tr\u1ee3<\/h2>\n\n

B\u1ea5t ch\u1ea5p ti\u1ec1m n\u0103ng c\u1ee7a m\u00ecnh, qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n RTS,S ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi nhi\u1ec1u tr\u1edf ng\u1ea1i \u0111\u00e1ng k\u1ec3. Thi\u1ebfu s\u1ef1 c\u1ea5p b\u00e1ch v\u00e0 t\u00e0i tr\u1ee3 cho nghi\u00ean c\u1ee9u v\u1ec1 b\u1ec7nh s\u1ed1t r\u00e9t, v\u00ec c\u0103n b\u1ec7nh n\u00e0y ch\u1ee7 y\u1ebfu \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c khu v\u1ef1c ngh\u00e8o kh\u00f3 \u1edf Ch\u00e2u Phi. Qu\u00e2n \u0111\u1ed9i, ban \u0111\u1ea7u t\u1ecf ra quan t\u00e2m \u0111\u1ebfn v\u1eafc-xin, sau \u0111\u00f3 \u0111\u00e3 r\u00fat l\u1ea1i s\u1ef1 h\u1ed7 tr\u1ee3.<\/p>\n\n

Nh\u1eefng r\u00e0o c\u1ea3n v\u1ec1 m\u1eb7t h\u1eadu c\u1ea7n<\/h2>\n\n

Vi\u1ec7c th\u1eed nghi\u1ec7m v\u1eafc-xin \u1edf c\u00e1c qu\u1ed1c gia Ch\u00e2u Phi t\u1ecf ra r\u1ea5t kh\u00f3 kh\u0103n. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi nh\u1eefng v\u1ea5n \u0111\u1ec1 v\u1ec1 m\u1eb7t h\u1eadu c\u1ea7n nh\u01b0 vi\u1ec7c th\u00e0nh l\u1eadp c\u00e1c ph\u00f2ng th\u00ed nghi\u1ec7m v\u00e0 ti\u1ebfn h\u00e0nh th\u1eed nghi\u1ec7m tr\u00ean tr\u1ebb nh\u1ecf. Qu\u00e1 tr\u00ecnh n\u00e0y m\u1ea5t h\u01a1n 10 n\u0103m \u0111\u1ec3 ho\u00e0n th\u00e0nh.<\/p>\n\n

Nh\u1eefng lo ng\u1ea1i v\u1ec1 s\u1ef1 an to\u00e0n v\u00e0 c\u00e1c th\u1eed nghi\u1ec7m m\u1edf r\u1ed9ng<\/h2>\n\n

C\u00e1c th\u1eed nghi\u1ec7m giai \u0111o\u1ea1n III cho th\u1ea5y nh\u1eefng k\u1ebft qu\u1ea3 kh\u1ea3 quan, nh\u01b0ng nh\u1eefng lo ng\u1ea1i v\u1ec1 b\u1ec7nh vi\u00eam m\u00e0ng n\u00e3o v\u00e0 t\u1eed vong \u1edf c\u00e1c b\u00e9 g\u00e1i \u0111\u00e3 \u0111\u01b0\u1ee3c ti\u00eam v\u1eafc-xin khi\u1ebfn WHO y\u00eau c\u1ea7u ti\u1ebfn h\u00e0nh m\u1ed9t th\u1eed nghi\u1ec7m tr\u00ean di\u1ec7n r\u1ed9ng h\u01a1n. \u0110i\u1ec1u n\u00e0y d\u1eabn \u0111\u1ebfn s\u1ef1 ch\u1eadm tr\u1ec5 trong b\u1ed1n n\u0103m v\u00e0 nh\u1eefng tr\u1edf ng\u1ea1i trong qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t.<\/p>\n\n

S\u1ef1 ch\u1ea5p thu\u1eadn v\u00e0 tri\u1ec3n khai<\/h2>\n\n

Sau khi xem x\u00e9t d\u1eef li\u1ec7u th\u1eed nghi\u1ec7m m\u1edf r\u1ed9ng, WHO \u0111\u00e3 ch\u00ednh th\u1ee9c khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i RTS,S v\u00e0o n\u0103m 2021. GAVI, m\u1ed9t c\u01a1 quan ph\u00e2n ph\u1ed1i v\u1eafc-xin to\u00e0n c\u1ea7u, \u0111\u00e3 c\u00f4ng b\u1ed1 kho\u1ea3n \u0111\u1ea7u t\u01b0 155,7 tri\u1ec7u \u0111\u00f4 la \u0111\u1ec3 tri\u1ec3n khai v\u1eafc-xin.<\/p>\n\n

So s\u00e1nh v\u1edbi ti\u1ebfn tr\u00ecnh ph\u00e1t tri\u1ec3n v\u1eafc-xin COVID-19<\/h2>\n\n

S\u1ef1 ph\u00e1t tri\u1ec3n nhanh ch\u00f3ng c\u1ee7a c\u00e1c lo\u1ea1i v\u1eafc-xin COVID-19 \u0111\u00e3 \u0111\u1eb7t ra c\u00e2u h\u1ecfi t\u1ea1i sao v\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t l\u1ea1i m\u1ea5t nhi\u1ec1u th\u1eddi gian \u0111\u1ebfn v\u1eady. C\u00e1c chuy\u00ean gia l\u01b0u \u00fd r\u1eb1ng s\u1ed1t r\u00e9t l\u00e0 m\u1ed9t m\u1ee5c ti\u00eau kh\u00f3 kh\u0103n h\u01a1n \u0111\u1ed1i v\u1edbi v\u1eafc-xin v\u00e0 hi\u1ec7u qu\u1ea3 th\u1ea5p h\u01a1n c\u1ee7a RTS,S c\u00f3 th\u1ec3 \u0111\u00e3 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh n\u00e0y. Ngo\u00e0i ra, c\u00e1c c\u00f4ng c\u1ee5 ch\u1ed1ng s\u1ed1t r\u00e9t hi\u1ec7n c\u00f3 \u0111\u00e3 l\u00e0m gi\u1ea3m c\u1ea3m gi\u00e1c c\u1ea5p b\u00e1ch \u0111\u1ed1i v\u1edbi v\u1eafc-xin.<\/p>\n\n

S\u1ef1 ch\u00eanh l\u1ec7ch trong t\u00e0i tr\u1ee3 v\u00e0 s\u1ef1 quan t\u00e2m<\/h2>\n\n

S\u1ef1 ch\u00eanh l\u1ec7ch v\u1ec1 t\u00e0i tr\u1ee3 v\u00e0 s\u1ef1 quan t\u00e2m gi\u1eefa b\u1ec7nh s\u1ed1t r\u00e9t v\u00e0 COVID-19 l\u00e0m n\u1ed5i b\u1eadt m\u00f4 h\u00ecnh l\u00e2u nay l\u00e0 s\u1ef1 th\u1edd \u01a1 \u0111\u1ed1i v\u1edbi nh\u1eefng c\u0103n b\u1ec7nh ch\u1ee7 y\u1ebfu \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c qu\u1ed1c gia c\u00f3 thu nh\u1eadp th\u1ea5p. Ngu\u1ed3n t\u00e0i tr\u1ee3 cho nghi\u00ean c\u1ee9u v\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t \u0111\u00e3 gi\u1ea3m, g\u00e2y nguy c\u01a1 cho vi\u1ec7c tri\u1ec3n khai RTS,S.<\/p>\n\n

C\u00e1c lo\u1ea1i v\u1eafc-xin th\u1ebf h\u1ec7 ti\u1ebfp theo<\/h2>\n\n

RTS,S \u0111\u00e3 m\u1edf \u0111\u01b0\u1eddng cho c\u00e1c lo\u1ea1i v\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t th\u1ebf h\u1ec7 ti\u1ebfp theo. V\u1eafc-xin R21 c\u1ee7a \u0110\u1ea1i h\u1ecdc Oxford \u0111ang cho th\u1ea5y nh\u1eefng h\u1ee9a h\u1eb9n trong c\u00e1c th\u1eed nghi\u1ec7m giai \u0111o\u1ea1n II. BioNTech, c\u00f4ng ty \u0111\u1ee9ng sau v\u1eafc-xin mRNA COVID-19, c\u0169ng \u0111ang ph\u00e1t tri\u1ec3n m\u1ed9t lo\u1ea1i v\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t s\u1eed d\u1ee5ng c\u00f9ng c\u00f4ng ngh\u1ec7.<\/p>\n\n

Tri\u1ec3n v\u1ecdng t\u01b0\u01a1ng lai<\/h2>\n\n

C\u00e1c chuy\u00ean gia l\u1ea1c quan r\u1eb1ng c\u00e1c lo\u1ea1i v\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t trong t\u01b0\u01a1ng lai s\u1ebd \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n nhanh h\u01a1n v\u00e0 hi\u1ec7u qu\u1ea3 h\u01a1n. Nh\u1eefng ti\u1ebfn b\u1ed9 trong c\u00f4ng ngh\u1ec7 mRNA v\u00e0 c\u00e1c c\u1ea3i ti\u1ebfn kh\u00e1c c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn nh\u1eefng b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 mang t\u00ednh c\u00e1ch m\u1ea1ng.<\/p>","protected":false},"excerpt":{"rendered":"

V\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t: M\u1ed9t b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 \u0111\u01b0\u1ee3c mong \u0111\u1ee3i t\u1eeb l\u00e2u Nh\u1eefng th\u00e1ch th\u1ee9c trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n Vi\u1ec7c ph\u00e1t tri\u1ec3n v\u1eafc-xin ph\u00f2ng s\u1ed1t r\u00e9t l\u00e0 m\u1ed9t…<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[463],"tags":[3370,2049,3706,2133,2862],"class_list":["post-18395","post","type-post","status-publish","format-standard","hentry","category-health-and-medicine","tag-medical-breakthrough","tag-scientific-research","tag-malaria","tag-global-health","tag-vaccine"],"_links":{"self":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/18395","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/comments?post=18395"}],"version-history":[{"count":1,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/18395\/revisions"}],"predecessor-version":[{"id":18396,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/18395\/revisions\/18396"}],"wp:attachment":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/media?parent=18395"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/categories?post=18395"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/tags?post=18395"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}