{"id":3275,"date":"2019-07-11T18:40:14","date_gmt":"2019-07-11T18:40:14","guid":{"rendered":"https:\/\/www.lifescienceart.com\/?p=3275"},"modified":"2019-07-11T18:40:14","modified_gmt":"2019-07-11T18:40:14","slug":"hiv-cure-stem-cell-transplant-breakthrough","status":"publish","type":"post","link":"https:\/\/www.lifescienceart.com\/vi\/science\/medicine\/hiv-cure-stem-cell-transplant-breakthrough\/","title":{"rendered":"\u0110i\u1ec1u tr\u1ecb HIV b\u1eb1ng gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c: \u0110\u1ed9t ph\u00e1 v\u00e0 \u00fd ngh\u0129a c\u1ee7a n\u00f3"},"content":{"rendered":"

\u0110i\u1ec1u tr\u1ecb HIV b\u1eb1ng gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c: \u0110\u1ed9t ph\u00e1 v\u00e0 \u00fd ngh\u0129a c\u1ee7a n\u00f3<\/h2>\n\n

Gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c: Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb HIV \u0111\u1ea7y h\u1ee9a h\u1eb9n<\/h2>\n\n

Trong m\u1ed9t di\u1ec5n bi\u1ebfn \u0111\u1ed9t ph\u00e1, m\u1ed9t ng\u01b0\u1eddi \u0111\u00e0n \u00f4ng 53 tu\u1ed5i \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 “b\u1ec7nh nh\u00e2n D\u00fcsseldorf” \u0111\u00e3 tr\u1edf th\u00e0nh ng\u01b0\u1eddi th\u1ee9 ba \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi HIV th\u00f4ng qua ph\u01b0\u01a1ng ph\u00e1p gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c. Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c t\u1ebf b\u00e0o g\u1ed1c v\u1edbi \u0111\u1ed9t bi\u1ebfn khi\u1ebfn ch\u00fang kh\u00e1ng HIV \u0111\u1ec3 thay th\u1ebf c\u00e1c t\u1ebf b\u00e0o t\u1ee7y x\u01b0\u01a1ng c\u1ee7a ch\u00ednh b\u1ec7nh nh\u00e2n.<\/p>\n\n

Nh\u1eefng c\u00e2u chuy\u1ec7n th\u00e0nh c\u00f4ng tr\u01b0\u1edbc \u0111\u00e2y<\/h2>\n\n

B\u1ec7nh nh\u00e2n D\u00fcsseldorf \u0111\u00e3 tham gia c\u00f9ng hai c\u00e1 nh\u00e2n kh\u00e1c \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi HIV b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c: Timothy Ray Brown, “b\u1ec7nh nh\u00e2n Berlin” v\u00e0 Adam Castillejo, “b\u1ec7nh nh\u00e2n London”. Nh\u1eefng tr\u01b0\u1eddng h\u1ee3p n\u00e0y \u0111\u00e3 ch\u1ee9ng minh ti\u1ec1m n\u0103ng c\u1ee7a ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y.<\/p>\n\n

H\u00e0nh tr\u00ecnh c\u1ee7a b\u1ec7nh nh\u00e2n D\u00fcsseldorf<\/h2>\n\n

\u0110\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc HIV v\u00e0o n\u0103m 2008 v\u00e0 b\u1ec7nh b\u1ea1ch c\u1ea7u v\u00e0o n\u0103m 2011, b\u1ec7nh nh\u00e2n D\u00fcsseldorf \u0111\u00e3 tr\u1ea3i qua ca gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c v\u00e0o n\u0103m 2013. C\u00e1c t\u1ebf b\u00e0o g\u1ed1c \u0111\u01b0\u1ee3c hi\u1ebfn t\u1eb7ng mang m\u1ed9t \u0111\u1ed9t bi\u1ebfn kh\u00e1ng HIV v\u00e0 sau khi ng\u1eebng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c kh\u00e1ng vi-r\u00fat (ART) v\u00e0o n\u0103m 2018, b\u1ec7nh nh\u00e2n v\u1eabn kh\u00f4ng m\u1eafc HIV trong h\u01a1n b\u1ed1n n\u0103m.<\/p>\n\n

Th\u00e1ch th\u1ee9c v\u00e0 h\u1ea1n ch\u1ebf<\/h2>\n\n

M\u1eb7c d\u00f9 gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c \u0111\u00e3 cho th\u1ea5y hi\u1ec7u qu\u1ea3 trong vi\u1ec7c ch\u1eefa kh\u1ecfi HIV, nh\u01b0ng \u0111i\u1ec1u quan tr\u1ecdng c\u1ea7n l\u01b0u \u00fd l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y c\u00f3 nguy c\u01a1 cao v\u00e0 kh\u00f4ng ph\u00f9 h\u1ee3p v\u1edbi t\u1ea5t c\u1ea3 b\u1ec7nh nh\u00e2n. Quy tr\u00ecnh n\u00e0y th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho nh\u1eefng ng\u01b0\u1eddi m\u1eafc c\u1ea3 HIV v\u00e0 ung th\u01b0, v\u00e0 kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng tr\u1edf th\u00e0nh ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa tr\u1ecb ph\u1ed5 bi\u1ebfn cho HIV n\u1ebfu kh\u00f4ng c\u00f3 ti\u1ebfn b\u1ed9 v\u1ec1 m\u1eb7t an to\u00e0n.<\/p>\n\n

Nghi\u00ean c\u1ee9u v\u00e0 ph\u00e1t tri\u1ec3n trong t\u01b0\u01a1ng lai<\/h2>\n\n

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111ang t\u00edch c\u1ef1c kh\u00e1m ph\u00e1 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ti\u1ebfp c\u1eadn thay th\u1ebf \u0111\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa kh\u1ecfi HIV. M\u1ed9t h\u01b0\u1edbng \u0111i \u0111\u1ea7y h\u1ee9a h\u1eb9n l\u00e0 bi\u1ebfn \u0111\u1ed5i gen c\u00e1c t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a ch\u00ednh m\u1ed9t ng\u01b0\u1eddi \u0111\u1ec3 ch\u00fang c\u00f3 \u0111\u1ed9t bi\u1ebfn kh\u00e1ng HIV, lo\u1ea1i b\u1ecf nhu c\u1ea7u gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c t\u1eeb ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng. Ngo\u00e0i ra, nh\u1eefng hi\u1ec3u bi\u1ebft thu \u0111\u01b0\u1ee3c t\u1eeb c\u00e1c tr\u01b0\u1eddng h\u1ee3p nh\u01b0 b\u1ec7nh nh\u00e2n D\u00fcsseldorf c\u00f3 th\u1ec3 gi\u00fap \u0111\u1ecbnh h\u01b0\u1edbng cho c\u00e1c nghi\u00ean c\u1ee9u trong t\u01b0\u01a1ng lai v\u00e0 c\u1ea3i thi\u1ec7n c\u00e1c chi\u1ebfn l\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb.<\/p>\n\n

Qu\u1ea3n l\u00fd HIV: Thu\u1ed1c kh\u00e1ng vi-r\u00fat v\u00e0 ph\u00f2ng ng\u1eeba<\/h2>\n\n

M\u1eb7c d\u00f9 ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa kh\u1ecfi HIV v\u1eabn c\u00f2n xa v\u1eddi \u0111\u1ed1i v\u1edbi h\u1ea7u h\u1ebft nh\u1eefng ng\u01b0\u1eddi m\u1eafc virus, nh\u01b0ng c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c kh\u00e1ng vi-r\u00fat (ART) \u0111\u00e3 c\u00e1ch m\u1ea1ng h\u00f3a vi\u1ec7c qu\u1ea3n l\u00fd HIV. ART \u1ee9c ch\u1ebf virus, ng\u0103n virus g\u00e2y b\u1ec7nh nghi\u00eam tr\u1ecdng v\u00e0 k\u00e9o d\u00e0i tu\u1ed5i th\u1ecd. C\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba, ch\u1eb3ng h\u1ea1n nh\u01b0 s\u1eed d\u1ee5ng bao cao su, d\u1ef1 ph\u00f2ng tr\u01b0\u1edbc ph\u01a1i nhi\u1ec5m (PrEP) v\u00e0 d\u1ef1 ph\u00f2ng sau ph\u01a1i nhi\u1ec5m (PEP), ti\u1ebfp t\u1ee5c \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c gi\u1ea3m l\u00e2y truy\u1ec1n HIV.<\/p>\n\n

T\u00e1c \u0111\u1ed9ng to\u00e0n c\u1ea7u c\u1ee7a HIV<\/h2>\n\n

HIV v\u1eabn l\u00e0 m\u1ed1i quan t\u00e2m y t\u1ebf to\u00e0n c\u1ea7u, v\u1edbi \u01b0\u1edbc t\u00ednh 38,4 tri\u1ec7u ng\u01b0\u1eddi tr\u00ean to\u00e0n th\u1ebf gi\u1edbi \u0111ang s\u1ed1ng chung v\u1edbi lo\u1ea1i virus n\u00e0y. Ph\u1ea7n l\u1edbn nh\u1eefng ng\u01b0\u1eddi n\u00e0y c\u01b0 tr\u00fa \u1edf c\u00e1c qu\u1ed1c gia thu nh\u1eadp th\u1ea5p v\u00e0 trung b\u00ecnh, n\u01a1i ti\u1ebfp c\u1eadn d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe v\u00e0 c\u00e1c ngu\u1ed3n l\u1ef1c r\u1ea5t h\u1ea1n ch\u1ebf. Nh\u1eefng n\u1ed7 l\u1ef1c nh\u1eb1m t\u0103ng c\u01b0\u1eddng ti\u1ebfp c\u1eadn v\u1edbi ART, c\u00e1c d\u1ecbch v\u1ee5 ph\u00f2ng ng\u1eeba v\u00e0 nghi\u00ean c\u1ee9u l\u00e0 r\u1ea5t c\u1ea7n thi\u1ebft \u0111\u1ec3 gi\u1ea3m g\u00e1nh n\u1eb7ng c\u1ee7a HIV tr\u00ean to\u00e0n c\u1ea7u.<\/p>\n\n

Hy v\u1ecdng cho t\u01b0\u01a1ng lai<\/h2>\n\n

Ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa kh\u1ecfi HIV cho b\u1ec7nh nh\u00e2n D\u00fcsseldorf v\u00e0 c\u00e1c nghi\u00ean c\u1ee9u \u0111ang di\u1ec5n ra v\u1ec1 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb HIV mang l\u1ea1i hy v\u1ecdng v\u1ec1 m\u1ed9t t\u01b0\u01a1ng lai khi HIV kh\u00f4ng c\u00f2n l\u00e0 t\u00ecnh tr\u1ea1ng \u0111e d\u1ecda t\u00ednh m\u1ea1ng. B\u1eb1ng c\u00e1ch ti\u1ebfp t\u1ee5c \u0111\u1ea7u t\u01b0 v\u00e0o nghi\u00ean c\u1ee9u v\u00e0 c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe, ch\u00fang ta c\u00f3 th\u1ec3 ti\u1ebfn g\u1ea7n h\u01a1n \u0111\u1ebfn m\u1ee5c ti\u00eau x\u00f3a b\u1ecf HIV v\u00e0 t\u00e1c \u0111\u1ed9ng t\u00e0n ph\u00e1 c\u1ee7a n\u00f3 \u0111\u1ed1i v\u1edbi c\u00e1c c\u00e1 nh\u00e2n v\u00e0 c\u1ed9ng \u0111\u1ed3ng tr\u00ean th\u1ebf gi\u1edbi.<\/p>","protected":false},"excerpt":{"rendered":"

\u0110i\u1ec1u tr\u1ecb HIV b\u1eb1ng gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c: \u0110\u1ed9t ph\u00e1 v\u00e0 \u00fd ngh\u0129a c\u1ee7a n\u00f3 Gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c: Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb HIV \u0111\u1ea7y h\u1ee9a h\u1eb9n Trong m\u1ed9t di\u1ec5n…<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[359],"tags":[3370,6333,6334,6335],"class_list":["post-3275","post","type-post","status-publish","format-standard","hentry","category-medicine","tag-medical-breakthrough","tag-hiv-cure","tag-stem-cell-transplant","tag-hiv-treatment"],"_links":{"self":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/3275","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/comments?post=3275"}],"version-history":[{"count":1,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/3275\/revisions"}],"predecessor-version":[{"id":3276,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/3275\/revisions\/3276"}],"wp:attachment":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/media?parent=3275"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/categories?post=3275"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/tags?post=3275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}