{"id":4444,"date":"2023-08-27T13:39:48","date_gmt":"2023-08-27T13:39:48","guid":{"rendered":"https:\/\/www.lifescienceart.com\/?p=4444"},"modified":"2023-08-27T13:39:48","modified_gmt":"2023-08-27T13:39:48","slug":"virtual-nanoscopy-exploring-biological-tissue-at-the-cellular-level","status":"publish","type":"post","link":"https:\/\/www.lifescienceart.com\/vi\/science\/microscopy\/virtual-nanoscopy-exploring-biological-tissue-at-the-cellular-level\/","title":{"rendered":"N\u1ed9i soi nano \u1ea3o: Kh\u00e1m ph\u00e1 c\u00e1c m\u00f4 sinh h\u1ecdc \u1edf c\u1ea5p \u0111\u1ed9 t\u1ebf b\u00e0o"},"content":{"rendered":"

N\u1ed9i soi nano \u1ea3o: Kh\u00e1m ph\u00e1 m\u00f4 sinh h\u1ecdc \u1edf c\u1ea5p \u0111\u1ed9 t\u1ebf b\u00e0o<\/h2>\n\n

N\u1ed9i soi nano \u1ea3o l\u00e0 g\u00ec?<\/h2>\n\n

N\u1ed9i soi nano \u1ea3o l\u00e0 m\u1ed9t c\u00f4ng ngh\u1ec7 m\u1edbi cho ph\u00e9p c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1o ra h\u00ecnh \u1ea3nh c\u00f3 th\u1ec3 thu ph\u00f3ng c\u1ee7a m\u00f4 sinh h\u1ecdc \u1edf c\u1ea5p \u0111\u1ed9 t\u1ebf b\u00e0o. C\u00f4ng ngh\u1ec7 n\u00e0y k\u1ebft h\u1ee3p h\u00e0ng ngh\u00ecn h\u00ecnh \u1ea3nh ri\u00eang l\u1ebb t\u1eeb k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed \u0111\u1ec3 t\u1ea1o ra m\u1ed9t t\u1ed5ng th\u1ec3 m\u1ea1ch l\u1ea1c v\u00e0 t\u01b0\u01a1ng t\u00e1c. \u0110i\u1ec1u n\u00e0y cho ph\u00e9p ng\u01b0\u1eddi xem kh\u00e1m ph\u00e1 c\u1ea5u tr\u00fac c\u1ee7a m\u00f4 v\u1edbi \u0111\u1ed9 chi ti\u1ebft ch\u01b0a t\u1eebng c\u00f3, t\u1eeb ch\u1ebf \u0111\u1ed9 xem to\u00e0n b\u1ed9 m\u00f4 cho \u0111\u1ebfn b\u00ean trong t\u1eebng t\u1ebf b\u00e0o.<\/p>\n\n

N\u1ed9i soi nano \u1ea3o ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o?<\/h2>\n\n

N\u1ed9i soi nano \u1ea3o b\u1eaft \u0111\u1ea7u b\u1eb1ng vi\u1ec7c thu th\u1eadp h\u00e0ng ngh\u00ecn h\u00ecnh \u1ea3nh ch\u1ed3ng l\u1ea5n nhau m\u1ed9t ch\u00fat b\u1eb1ng k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed. Sau \u0111\u00f3, c\u00e1c h\u00ecnh \u1ea3nh n\u00e0y \u0111\u01b0\u1ee3c gh\u00e9p l\u1ea1i v\u1edbi nhau b\u1eb1ng m\u1ed9t ph\u1ea7n m\u1ec1m t\u1ef1 \u0111\u1ed9ng. Ph\u1ea7n m\u1ec1m s\u1eed d\u1ee5ng si\u00eau d\u1eef li\u1ec7u v\u1ec1 h\u01b0\u1edbng c\u1ee7a t\u1eebng h\u00ecnh \u1ea3nh v\u00e0 m\u1ed9t thu\u1eadt to\u00e1n so s\u00e1nh c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m t\u01b0\u01a1ng t\u1ef1 trong m\u1ed7i h\u00ecnh \u1ea3nh \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh ch\u00ednh x\u00e1c v\u1ecb tr\u00ed c\u1ea7n \u0111\u1eb7t c\u00e1c h\u00ecnh \u1ea3nh \u0111\u00f3.<\/p>\n\n

H\u00ecnh \u1ea3nh thu \u0111\u01b0\u1ee3c l\u00e0 m\u1ed9t t\u1ec7p kh\u1ed5ng l\u1ed3 c\u00f3 th\u1ec3 ph\u00f3ng to v\u00e0 thu nh\u1ecf \u0111\u1ec3 hi\u1ec3n th\u1ecb c\u00e1c m\u1ee9c \u0111\u1ed9 chi ti\u1ebft kh\u00e1c nhau. V\u00ed d\u1ee5: h\u00ecnh \u1ea3nh ph\u00f4i c\u00e1 ng\u1ef1a v\u1eb1n \u0111\u01b0\u1ee3c hi\u1ec3n th\u1ecb trong b\u00e0i vi\u1ebft bao g\u1ed3m h\u01a1n 26.000 h\u00ecnh \u1ea3nh ri\u00eang l\u1ebb v\u00e0 c\u00f3 t\u1ed5ng tr\u1ecdng l\u01b0\u1ee3ng l\u00e0 281 gigapixel. \u0110i\u1ec1u n\u00e0y cho ph\u00e9p ng\u01b0\u1eddi xem chuy\u1ec3n t\u1eeb h\u00ecnh \u1ea3nh thu nh\u1ecf c\u1ee7a to\u00e0n b\u1ed9 ph\u00f4i sang ch\u1ebf \u0111\u1ed9 xem chi ti\u1ebft c\u00e1c c\u1ea5u tr\u00fac, ch\u1eb3ng h\u1ea1n nh\u01b0 nh\u00e2n, b\u00ean trong m\u1ed9t t\u1ebf b\u00e0o c\u1ee5 th\u1ec3.<\/p>\n\n

L\u1ee3i \u00edch c\u1ee7a n\u1ed9i soi nano \u1ea3o<\/h2>\n\n

N\u1ed9i soi nano \u1ea3o cung c\u1ea5p m\u1ed9t s\u1ed1 l\u1ee3i \u00edch so v\u1edbi k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed truy\u1ec1n th\u1ed1ng. \u0110\u1ea7u ti\u00ean, c\u00f4ng ngh\u1ec7 n\u00e0y cho ph\u00e9p c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1o ra ch\u1ebf \u0111\u1ed9 xem 3D ho\u00e0n ch\u1ec9nh c\u1ee7a m\u1ed9t m\u1eabu m\u00f4. \u0110i\u1ec1u n\u00e0y tr\u00e1i ng\u01b0\u1ee3c v\u1edbi k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed truy\u1ec1n th\u1ed1ng, ch\u1ec9 c\u00f3 th\u1ec3 ch\u1ee5p \u1ea3nh 2D c\u00e1c v\u00f9ng m\u00f4 nh\u1ecf.<\/p>\n\n

Th\u1ee9 hai, n\u1ed9i soi nano \u1ea3o cho ph\u00e9p c\u00e1c nh\u00e0 khoa h\u1ecdc kh\u00e1m ph\u00e1 c\u00e1c m\u1eabu m\u00f4 theo c\u00e1ch kh\u00f4ng ph\u00e1 h\u1ee7y. K\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed truy\u1ec1n th\u1ed1ng y\u00eau c\u1ea7u ph\u1ea3i b\u1ea3o qu\u1ea3n m\u1eabu theo c\u00e1ch c\u00f3 th\u1ec3 l\u00e0m h\u1ecfng c\u1ea5u tr\u00fac c\u1ee7a m\u1eabu. M\u1eb7t kh\u00e1c, n\u1ed9i soi nano \u1ea3o kh\u00f4ng y\u00eau c\u1ea7u b\u1ea5t k\u1ef3 ch\u1ebf ph\u1ea9m m\u1eabu n\u00e0o, do \u0111\u00f3 c\u00f4ng ngh\u1ec7 n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 nghi\u00ean c\u1ee9u m\u00f4 s\u1ed1ng.<\/p>\n\n

Th\u1ee9 ba, n\u1ed9i soi nano \u1ea3o nhanh h\u01a1n nhi\u1ec1u so v\u1edbi k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed truy\u1ec1n th\u1ed1ng. C\u00f3 th\u1ec3 m\u1ea5t nhi\u1ec1u gi\u1edd ho\u1eb7c th\u1eadm ch\u00ed nhi\u1ec1u ng\u00e0y \u0111\u1ec3 thu th\u1eadp v\u00e0 x\u1eed l\u00fd m\u1ed9t h\u00ecnh \u1ea3nh k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed \u0111\u01a1n l\u1ebb. M\u1eb7t kh\u00e1c, n\u1ed9i soi nano \u1ea3o c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 t\u1ea1o ra h\u00ecnh \u1ea3nh 3D ho\u00e0n ch\u1ec9nh c\u1ee7a m\u1ed9t m\u1eabu m\u00f4 ch\u1ec9 trong v\u00e0i ph\u00fat.<\/p>\n\n

C\u00e1c \u1ee9ng d\u1ee5ng c\u1ee7a n\u1ed9i soi nano \u1ea3o<\/h2>\n\n

N\u1ed9i soi nano \u1ea3o c\u00f3 nhi\u1ec1u \u1ee9ng d\u1ee5ng trong nghi\u00ean c\u1ee9u sinh h\u1ecdc. C\u00f4ng ngh\u1ec7 n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 nghi\u00ean c\u1ee9u c\u1ea5u tr\u00fac c\u1ee7a t\u1ebf b\u00e0o, m\u00f4 v\u00e0 c\u01a1 quan. C\u00f4ng ngh\u1ec7 n\u00e0y c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 theo d\u00f5i s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ph\u00f4i v\u00e0 \u0111\u1ec3 nghi\u00ean c\u1ee9u t\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c v\u00e0 \u0111\u1ed9c t\u1ed1 \u0111\u1ed1i v\u1edbi t\u1ebf b\u00e0o.<\/p>\n\n

Trong b\u00e0i vi\u1ebft, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 s\u1eed d\u1ee5ng n\u1ed9i soi nano \u1ea3o \u0111\u1ec3 ph\u00e2n t\u00edch ph\u00f4i c\u00e1 ng\u1ef1a v\u1eb1n, m\u00f4 da ng\u01b0\u1eddi, ph\u00f4i chu\u1ed9t v\u00e0 t\u1ebf b\u00e0o th\u1eadn chu\u1ed9t. H\u1ecd ph\u00e1t hi\u1ec7n ra r\u1eb1ng n\u1ed9i soi nano \u1ea3o c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh c\u00e1c c\u1ea5u tr\u00fac m\u1edbi trong t\u1ebf b\u00e0o v\u00e0 theo d\u00f5i chuy\u1ec3n \u0111\u1ed9ng c\u1ee7a t\u1ebf b\u00e0o theo th\u1eddi gian.<\/p>\n\n

K\u1ebft lu\u1eadn<\/h2>\n\n

N\u1ed9i soi nano \u1ea3o l\u00e0 m\u1ed9t c\u00f4ng c\u1ee5 m\u1edbi m\u1ea1nh m\u1ebd \u0111ang c\u00e1ch m\u1ea1ng h\u00f3a c\u00e1ch c\u00e1c nh\u00e0 khoa h\u1ecdc nghi\u00ean c\u1ee9u m\u00f4 sinh h\u1ecdc. C\u00f4ng ngh\u1ec7 n\u00e0y cung c\u1ea5p m\u1ed9t s\u1ed1 l\u1ee3i th\u1ebf so v\u1edbi k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed truy\u1ec1n th\u1ed1ng, bao g\u1ed3m kh\u1ea3 n\u0103ng t\u1ea1o ra h\u00ecnh \u1ea3nh 3D ho\u00e0n ch\u1ec9nh c\u1ee7a c\u00e1c m\u1eabu m\u00f4, kh\u00e1m ph\u00e1 c\u00e1c m\u1eabu m\u00f4 theo c\u00e1ch kh\u00f4ng ph\u00e1 h\u1ee7y v\u00e0 th\u1ef1c hi\u1ec7n nhanh h\u01a1n nhi\u1ec1u so v\u1edbi k\u00ednh hi\u1ec3n vi \u0111i\u1ec7n t\u1eed truy\u1ec1n th\u1ed1ng. Do \u0111\u00f3, n\u1ed9i soi nano \u1ea3o \u0111\u01b0\u1ee3c k\u1ef3 v\u1ecdng s\u1ebd \u0111\u00f3ng m\u1ed9t vai tr\u00f2 quan tr\u1ecdng trong nghi\u00ean c\u1ee9u sinh h\u1ecdc trong nh\u1eefng n\u0103m t\u1edbi.<\/p>","protected":false},"excerpt":{"rendered":"

N\u1ed9i soi nano \u1ea3o: Kh\u00e1m ph\u00e1 m\u00f4 sinh h\u1ecdc \u1edf c\u1ea5p \u0111\u1ed9 t\u1ebf b\u00e0o N\u1ed9i soi nano \u1ea3o l\u00e0 g\u00ec? N\u1ed9i soi nano \u1ea3o l\u00e0 m\u1ed9t c\u00f4ng ngh\u1ec7 m\u1edbi cho…<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4878],"tags":[8082,97,8081,8083,9,8080],"class_list":["post-4444","post","type-post","status-publish","format-standard","hentry","category-microscopy","tag-cellular-imaging","tag-science","tag-electron-microscopy","tag-biological-tissue","tag-art","tag-virtual-nanoscopy"],"_links":{"self":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/4444","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/comments?post=4444"}],"version-history":[{"count":1,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/4444\/revisions"}],"predecessor-version":[{"id":4445,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/posts\/4444\/revisions\/4445"}],"wp:attachment":[{"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/media?parent=4444"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/categories?post=4444"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifescienceart.com\/vi\/wp-json\/wp\/v2\/tags?post=4444"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}